Technology of deep brain stimulation: current status and future directions

JK Krauss, N Lipsman, T Aziz, A Boutet… - Nature Reviews …, 2021 - nature.com
Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Deep brain stimulation: current challenges and future directions

AM Lozano, N Lipsman, H Bergman, P Brown… - Nature Reviews …, 2019 - nature.com
The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …

Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics

S Chen, AZ Weitemier, X Zeng, L He, X Wang, Y Tao… - Science, 2018 - science.org
Optogenetics has revolutionized the experimental interrogation of neural circuits and holds
promise for the treatment of neurological disorders. It is limited, however, because visible …

[HTML][HTML] An introduction to high intensity focused ultrasound: systematic review on principles, devices, and clinical applications

Z Izadifar, Z Izadifar, D Chapman, P Babyn - Journal of clinical medicine, 2020 - mdpi.com
Ultrasound can penetrate deep into tissues and interact with human tissue via thermal and
mechanical mechanisms. The ability to focus an ultrasound beam and its energy onto …

[HTML][HTML] Optimal deep brain stimulation sites and networks for stimulation of the fornix in Alzheimer's disease

AS Ríos, S Oxenford, C Neudorfer, K Butenko… - Nature …, 2022 - nature.com
Deep brain stimulation (DBS) to the fornix is an investigational treatment for patients with
mild Alzheimer's Disease. Outcomes from randomized clinical trials have shown that …

Connectivity predicts deep brain stimulation outcome in P arkinson disease

A Horn, M Reich, J Vorwerk, N Li, G Wenzel… - Annals of …, 2017 - Wiley Online Library
Objective The benefit of deep brain stimulation (DBS) for Parkinson disease (PD) may
depend on connectivity between the stimulation site and other brain regions, but which …

The physics of brain network structure, function and control

CW Lynn, DS Bassett - Nature Reviews Physics, 2019 - nature.com
The brain is characterized by heterogeneous patterns of structural connections supporting
unparalleled feats of cognition and a wide range of behaviours. New non-invasive imaging …

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 4 …

RV Milev, P Giacobbe, SH Kennedy… - The Canadian …, 2016 - journals.sagepub.com
Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

[HTML][HTML] Cortico-striatal-thalamic loop circuits of the salience network: a central pathway in psychiatric disease and treatment

SK Peters, K Dunlop, J Downar - Frontiers in systems neuroscience, 2016 - frontiersin.org
The salience network (SN) plays a central role in cognitive control by integrating sensory
input to guide attention, attend to motivationally salient stimuli and recruit appropriate …

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

JA Obeso, M Stamelou, CG Goetz, W Poewe… - Movement …, 2017 - Wiley Online Library
This article reviews and summarizes 200 years of Parkinson's disease. It comprises a
relevant history of Dr. James Parkinson's himself and what he described accurately and …