With the advances in biomedical technologies, natural products have attracted substantial
public attention in the area of drug discovery. Flavonoids are a class of active natural …

Background and Objectives. Human beings have used natural products as one of the
pharmaceutical sources to improve human health for thousands of years. Phytochemical …

Ethnopharmacological relevance Paeoniflorin (PF) was found to exhibit renal protection
from diabetic kidney disease (DKD) in previous trials, but its specific mechanism remains to …

Diabetic kidney disease (DKD) is the major reason of chronic kidney disease (CKD)-caused
end-stage renal failure (ESRF), and leads to high mortality worldwide. At present, the …

Diabetic nephropathy (DN) is one of the most serious complications of diabetes and the
main cause of end-stage renal failure. Rhubarb is a widely used traditional Chinese herb …

Rationale and objective A causal relationship concerning coffee intake and diabetic
nephropathy (DN) is controversial. We conducted a Mendelian randomization study to …

The anti‐inflammatory activity of cirsilineol in in vivo condition was assessed by measuring
the relative organ weight, lung dry/wet weight ratio, protein concentration, and infiltration of …

Diabetes mellitus (DM) is a widespread metabolic disorder with a yearly 6.7 million deaths
worldwide. Several treatment options are available but with common side effects like weight …

Introduction: As a traditional Chinese medicine, Abelmoschus manihot (L.) in the form of
Huangkui (HK) capsule has been used as a medication for kidney diseases, including …

Diabetic nephropathy (DN) is one of the serious complications of diabetes mellitus, primarily
arising from type 2 diabetes (T2DM), and can progress to chronic kidney disease (CKD) and …