Ribosome-associated quality-control mechanisms from bacteria to humans
S Filbeck, F Cerullo, S Pfeffer, CAP Joazeiro - Molecular cell, 2022 - cell.com
Ribosome-associated quality-control (RQC) surveys incomplete nascent polypeptides
produced by interrupted translation. Central players in RQC are the human ribosome-and …
produced by interrupted translation. Central players in RQC are the human ribosome-and …
Eukaryotic mismatch repair in relation to DNA replication
TA Kunkel, DA Erie - Annual review of genetics, 2015 - annualreviews.org
Three processes act in series to accurately replicate the eukaryotic nuclear genome. The
major replicative DNA polymerases strongly prevent mismatch formation, occasional …
major replicative DNA polymerases strongly prevent mismatch formation, occasional …
Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue
Ribosome stalling during translation is detrimental to cellular fitness, but how this is sensed
and elicits recycling of ribosomal subunits and quality control of associated mRNA and …
and elicits recycling of ribosomal subunits and quality control of associated mRNA and …
Genetic and genomic basis of the mismatch repair system involved in Lynch syndrome
K Tamura, M Kaneda, M Futagawa, M Takeshita… - International journal of …, 2019 - Springer
Lynch syndrome is a cancer-predisposing syndrome inherited in an autosomal-dominant
manner, wherein colon cancer and endometrial cancer develop frequently in the family, it …
manner, wherein colon cancer and endometrial cancer develop frequently in the family, it …
Lynch syndrome, molecular mechanisms and variant classification
Patients with the heritable cancer disease, Lynch syndrome, carry germline variants in the
MLH1, MSH2, MSH6 and PMS2 genes, encoding the central components of the DNA …
MLH1, MSH2, MSH6 and PMS2 genes, encoding the central components of the DNA …
Roles for mismatch repair family proteins in promoting meiotic crossing over
CM Manhart, E Alani - DNA repair, 2016 - Elsevier
The mismatch repair (MMR) family complexes Msh4-Msh5 and Mlh1-Mlh3 act with Exo1 and
Sgs1-Top3-Rmi1 in a meiotic double strand break repair pathway that results in the …
Sgs1-Top3-Rmi1 in a meiotic double strand break repair pathway that results in the …
Protecting DNA from errors and damage: an overview of DNA repair mechanisms in plants compared to mammals
CP Spampinato - Cellular and Molecular Life Sciences, 2017 - Springer
The genome integrity of all organisms is constantly threatened by replication errors and DNA
damage arising from endogenous and exogenous sources. Such base pair anomalies must …
damage arising from endogenous and exogenous sources. Such base pair anomalies must …
Xer site specific recombination: double and single recombinase systems
F Castillo, A Benmohamed, G Szatmari - Frontiers in microbiology, 2017 - frontiersin.org
The separation and segregation of newly replicated bacterial chromosomes can be
constrained by the formation of circular chromosome dimers caused by crossing over during …
constrained by the formation of circular chromosome dimers caused by crossing over during …
Temozolomide and pituitary tumors: current understanding, unresolved issues, and future directions
LV Syro, F Rotondo, M Camargo, LD Ortiz… - Frontiers in …, 2018 - frontiersin.org
Temozolomide, an alkylating agent, initially used in the treatment of gliomas was expanded
to include pituitary tumors in 2006. After 12 years of use, temozolomide has shown a notable …
to include pituitary tumors in 2006. After 12 years of use, temozolomide has shown a notable …