In the past 15 years, B cells have been rediscovered to be not merely bystanders but rather
active participants in autoimmune aetiology. This has been fuelled in part by the clinical …

Among human leukocyte antigen (HLA)-associated disorders, celiac disease has an
immunopathogenesis that is particularly well understood. The condition is characterized by …

While the antibody response to SARS-CoV-2 has been extensively studied in blood,
relatively little is known about the antibody response in saliva and its relationship to systemic …

B cells, which are critical for intestinal homeostasis, remain understudied in ulcerative colitis
(UC). In this study, we recruited three cohorts of patients with UC (primary cohort, n= 145; …

Antibodies produced by antibody-secreting plasma cells (ASCs) underlie multiple forms of
long-lasting immunity. Here we examined the mechanisms regulating ASC turnover and …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

The hematopoietic system seeds the CNS with microglial progenitor cells during the fetal
period, but the subsequent cell generation dynamics and maintenance of this population …

Resident memory T (Trm) cells stably occupy tissues and cannot be sampled in superficial
venous blood. Trm cells are heterogeneous but collectively constitute the most abundant …

Various immune mechanisms are deployed in the mucosa to confront the immense diversity
of resident bacteria. A substantial fraction of the commensal microbiota is coated with …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …