Immunotherapy in head and neck cancer: where do we stand?

NG Vallianou, A Evangelopoulos, D Kounatidis… - Current Oncology …, 2023 - Springer
Abstract Purposeof Review Head and neck cancer (HNC) comprises a group of
malignancies, amongst which squamous cell carcinoma accounts for more than 90% of the …

[HTML][HTML] Insights into gold nanoparticles possibilities for diagnosis and treatment of the head and neck upper aerodigestive tract cancers

LM Andrade, GMJ Costa - Cancers, 2023 - mdpi.com
Simple Summary The application of nanotechnology in medicine has caught the scientific
community's attention. Nevertheless, staying updated about its countless possibilities has …

[HTML][HTML] The role of nanotherapy in head and neck squamous cell carcinoma by targeting tumor microenvironment

Y Zhang, P Dong, L Yang - Frontiers in Immunology, 2023 - frontiersin.org
Head and neck squamous cell carcinomas (HNSCCs) refers to a group of highly malignant
and pathogenically complex tumors. Traditional treatment methods include surgery …

[HTML][HTML] Therapeutic Vaccination in Head and Neck Squamous Cell Carcinoma—A Review

K Devaraja, S Aggarwal, M Singh - Vaccines, 2023 - mdpi.com
Therapeutic vaccination is one of the most effective immunotherapeutic approaches, second
only to immune checkpoint inhibitors (ICIs), which have already been approved for clinical …

[HTML][HTML] Implications of oral dysbiosis and HPV infection in head and neck cancer: from molecular and cellular mechanisms to early diagnosis and therapy

M Constantin, MC Chifiriuc, G Mihaescu… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Head and neck cancer (HNC) is the sixth most common type of cancer, with more than half a
million new cases annually. This review focuses on the role of oral dysbiosis and HPV …

[HTML][HTML] The Role of Different Immunocompetent Cell Populations in the Pathogenesis of Head and Neck Cancer—Regulatory Mechanisms of Pro-and Anti-Cancer …

K Starska-Kowarska - Cancers, 2023 - mdpi.com
Simple Summary According to the latest GLOBOCAN data, head and neck squamous cell
carcinoma (HNSCC) represents the sixth most prevalent human malignancy. Recent studies …

Transcriptomic analysis of Porphyromonas gingivalis‐infected head and neck cancer cells: Identification of PLAU as a candidate prognostic biomarker

M Hamada, H Inaba, K Nishiyama… - Journal of Cellular …, 2024 - Wiley Online Library
Periodontal disease is a risk factor for head and neck squamous cell carcinoma (HNSCC),
and Porphyromonas gingivalis, a major periodontal pathogen, has been identified as a …

[HTML][HTML] IL17RB and IL17REL Expression Are Associated with Improved Prognosis in HPV-Infected Head and Neck Squamous Cell Carcinomas

Y Sun, MAAK Khan, S Mangiola, AD Barrow - Pathogens, 2023 - mdpi.com
Changes in the cellular secretome are implicated in virus infection, malignancy, and anti-
tumor immunity. We analyzed the association between transcriptional signatures (TS) from …

Prognostic significance and immune escape implication of tumor-infiltrating neutrophil plasticity in human head and neck squamous cell carcinoma

X Zhu, Y Heng, D Zhang, D Tang, J Zhou, H Lin, J Ma… - Human Cell, 2024 - Springer
Tumor-infiltrating neutrophils play a crucial role in the progression of head and neck
squamous cell carcinoma (HNSCC). Here, we aimed to statistically quantify the plasticity of …

IDO1 correlates with the immune landscape of head and neck squamous cell carcinoma: a study based on bioinformatics analyses

GV Gkountana, L Wang, M Giacomini… - Frontiers in Oral …, 2024 - frontiersin.org
Background Head and neck squamous cell carcinoma (HNSCCs) is a common cancer type
with a high mortality rate and poor prognosis. Recent studies have focused on the role of …