Immune checkpoint inhibitor use in head and neck squamous cell carcinoma: the current landscape and future perspectives

ER Gatfield, J Tadross, W Ince - Future Oncology, 2024 - Taylor & Francis
Article highlights Immune checkpoint inhibitors Immune checkpoint inhibitor (ICI) therapies
most commonly target PD-1, PD-L1 or CTLA-4, but novel targets include TIGIT, TIM3 and OX …

Prognostic significance and immune escape implication of tumor-infiltrating neutrophil plasticity in human head and neck squamous cell carcinoma

X Zhu, Y Heng, D Zhang, D Tang, J Zhou, H Lin, J Ma… - Human Cell, 2024 - Springer
Tumor-infiltrating neutrophils play a crucial role in the progression of head and neck
squamous cell carcinoma (HNSCC). Here, we aimed to statistically quantify the plasticity of …

[HTML][HTML] Advances in tumor immune microenvironment of head and neck squamous cell carcinoma: A review of literature

Q Hong, S Ding, C Xing, Z Mu - Medicine, 2024 - journals.lww.com
Squamous cell carcinoma is seen as principal malignancy of head and neck. Tumor immune
microenvironment plays a vital role in the occurrence, development and treatment of head …

NUP62CL as an Immunological and Prognostic Biomarker of Oral Squamous Cell Carcinoma

X Yu, L Xu, Y Zhou, X Zhou, L Yang… - Journal of Inflammation …, 2023 - Taylor & Francis
Background Oral squamous cell carcinoma (OSCC) is the most common head and neck
malignancy with a high mortality rate and poor prognosis. The exploration and …

[HTML][HTML] RNA-binding protein HuR reprograms immune T cells and promotes oral squamous cell carcinoma

M Majumder, H Janakiraman, P Chakraborty… - Oral oncology …, 2024 - Elsevier
Hu Antigen R, also known as ELAVL1 (HuR), is a key posttranscriptional regulator in
eukaryotic cells. HuR overexpression promotes several malignancies, including head and …

[HTML][HTML] A novel immune-related prognostic model with surgical status to predict tumor immune cell infiltration and drug sensitivity in head and neck squamous cell …

L Wang, X Yu, H Li, C Wang - Biochemistry and Biophysics Reports, 2023 - Elsevier
Tumor-infiltrating immune cells (TICs) affect tumorigenesis and tumor development in head
and neck squamous cell carcinoma (HNSCC). We constructed a novel predictive model for …

[PDF][PDF] Identification of simple and reliable prognostic markers in oral cancer

A Wahab - 2024 - helda.helsinki.fi
Oral squamous cell carcinoma (OSCC), a subsite of head and neck squamous cell
carcinoma (HNSCC) has presented with an increased incidence in many countries. Oral …

Analyse der Immunzellinfiltration des Tumormikromilieus und seiner prognostischen Relevanz bei Patienten mit einem Plattenepithelkarzinom des Kopf-Hals …

M Knebel - 2023 - publikationen.sulb.uni-saarland.de
Plattenepithelkarzinome der Kopf-Hals-Region (head and neck squamous cell carcinoma,
HNSCC) stellen mit jährlich 550.000 neu diagnostizierten Erkrankungen und 380.000 …