[HTML][HTML] Circular RNAs as potential biomarkers in breast cancer

FDE De Palma, F Salvatore, JG Pol, G Kroemer… - Biomedicines, 2022 - mdpi.com
Due to the high heterogeneity and initially asymptomatic nature of breast cancer (BC), the
management of this disease depends on imaging together with immunohistochemical and …

[HTML][HTML] Critical roles of circular RNA in tumor metastasis via acting as a sponge of miRNA/isomiR

L Guo, L Jia, L Luo, X Xu, Y Xiang, Y Ren… - International Journal of …, 2022 - mdpi.com
Circular RNAs (circRNAs), a class of new endogenous non-coding RNAs (ncRNAs), are
closely related to the carcinogenic process and play a critical role in tumor metastasis …

[HTML][HTML] CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer

T Jiang, H Wang, L Liu, H Song, Y Zhang, J Wang… - Molecular cancer, 2021 - Springer
Background Accumulating studies have revealed that aberrant expression of circular RNAs
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …

[HTML][HTML] Circular RNA circLMO1 suppresses cervical cancer growth and metastasis by triggering miR-4291/ACSL4-mediated ferroptosis

R Ou, S Lu, L Wang, Y Wang, M Lv, T Li, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Background: A number of studies have demonstrated that circular RNA (circRNA) plays a
critical role in tumorigenesis and tumor progression. However, the biological effects of most …

[HTML][HTML] Emerging role of circular RNAs in hepatocellular carcinoma immunotherapy

T Abaza, MKA El-Aziz, KA Daniel, P Karousi… - International Journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is a highly fatal malignancy with limited therapeutic options
and high recurrence rates. Recently, immunotherapeutic agents such as immune checkpoint …

[HTML][HTML] Circular RNAs: implications of signaling pathways and bioinformatics in human cancer

F Hu, Y Peng, X Fan, X Zhang, Z Jin - Cancer Biology & Medicine, 2023 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) form a class of endogenous single-stranded RNA transcripts that
are widely expressed in eukaryotic cells. These RNAs mediate post-transcriptional control of …

[HTML][HTML] Identification of Novel Circular RNAs of the Human Protein Arginine Methyltransferase 1 (PRMT1) Gene, Expressed in Breast Cancer Cells

M Papatsirou, MA Diamantopoulos, K Katsaraki… - Genes, 2022 - mdpi.com
Circular RNAs (circRNAs) constitute a type of RNA formed through back-splicing. In breast
cancer, circRNAs are implicated in tumor onset and progression. Although histone …

[HTML][HTML] The dual role of circular RNAs as miRNA sponges in breast cancer and colon cancer

J Huang, S Yu, L Ding, L Ma, H Chen, H Zhou, Y Zou… - Biomedicines, 2021 - mdpi.com
Breast cancer (BC) and colon cancer (CRC) are the two most deadly cancers in the world.
These cancers partly share the same genetic background and are partially regulated by the …

[HTML][HTML] Circular RNA circCCDC85A inhibits breast cancer progression via acting as a miR-550a-5p sponge to enhance MOB1A expression

L Meng, S Chang, Y Sang, P Ding, L Wang… - Breast Cancer …, 2022 - Springer
Background A growing body of evidence indicates that abnormal expression of circular
RNAs (circRNAs) plays a crucial role by acting as molecular sponges of microRNAs …

Tumor-derived or non-tumor-derived exosomal noncodingRNAs and signaling pathways in tumor microenvironment

Y Wu, D Niu, S Deng, X Lei, Z Xie, X Yang - International …, 2022 - Elsevier
The tumor microenvironment (TME) involved in multiple pathological processes of tumors is
highly complex. Exosomes, as organelles, can be produced by some cells in the TME and …