[HTML][HTML] Immune response and treatment targets of chronic hepatitis B virus infection: Innate and adaptive immunity

P Zheng, Y Dou, Q Wang - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Chronic hepatitis B virus (HBV) infection is a major global public health risk that threatens
human life and health, although the number of vaccinated people has increased. The …

[HTML][HTML] Crucial role of T cells in NAFLD-related disease: A review and prospect

T Mao, R Yang, Y Luo, K He - Frontiers in Endocrinology, 2022 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) includes a series of hepatic manifestations, starting
with liver steatosis and potentially evolving towards nonalcoholic steatohepatitis (NASH) …

Itaconate inhibits CD103+ TRM cells and alleviates hepatobiliary injury in mouse models of primary sclerosing cholangitis

Y Li, B Li, X Xiao, Q Qian, R Wang, Z Lyu, R Chen… - Hepatology, 2024 - journals.lww.com
Itaconate inhibits CD103+ TRM cells and alleviates hepatobil... : Hepatology Itaconate inhibits
CD103+ TRM cells and alleviates hepatobiliary injury in mouse models of primary sclerosing …

[HTML][HTML] Virus-specific TRM cells of both donor and recipient origin reside in human kidney transplants

DM Hullegie-Peelen, HT Mora, DA Hesselink… - JCI insight, 2023 - ncbi.nlm.nih.gov
Tissue-resident lymphocytes (TRLs) are critical for local protection against viral pathogens in
peripheral tissue. However, it is unclear if TRLs perform a similar role in transplanted organs …

Τ cell-mediated adaptive immunity in the transition from metabolic dysfunction-associated steatohepatitis to hepatocellular carcinoma

G Papadopoulos, E Giannousi, AP Avdi… - Frontiers in Cell and …, 2024 - frontiersin.org
Metabolic dysfunction-associated steatohepatitis (MASH) is the progressed version of
metabolic dysfunction-associated steatotic liver disease (MASLD) characterized by …

[HTML][HTML] From NAFLD to NASH: Understanding the spectrum of non-alcoholic liver diseases and their consequences

AM Samy, MA Kandeil, D Sabry, AA Abdel-Ghany… - Heliyon, 2024 - cell.com
Non-alcoholic fatty liver disease (NAFLD) has become one of the most frequent chronic liver
diseases worldwide in recent decades. Metabolic diseases like excessive blood glucose …

Interferon‐γ+ Th1 activates intrahepatic resident memory T cells to promote HBsAg loss by inducing M1 macrophage polarization

L Wu, H Deng, X Feng, D Xie, Z Li… - Journal of Medical …, 2024 - Wiley Online Library
The immune mechanism underlying hepatitis B surface antigen (HBsAg) loss, particularly
type I inflammatory response, during pegylated interferon‐α (PEG‐IFN) therapy remains …

Tissue-Resident Memory T Cells in Gastrointestinal Cancers: Prognostic Significance and Therapeutic Implications

H Sato, S Meng, T Hara, Y Tsuji, Y Arao, K Sasaki… - Biomedicines, 2024 - mdpi.com
Gastrointestinal cancers, which include a variety of esophageal and colorectal
malignancies, present a global health challenge and require effective treatment strategies …

[HTML][HTML] Abnormally primed CD8 T cells: The Achilles' heel of CHB

X Chen, X Liu, Y Jiang, N Xia, C Liu, W Luo - Frontiers in Immunology, 2023 - frontiersin.org
Chronic hepatitis B virus (HBV) infection continues to be a significant public health
challenge, and more than 250 million people around world are infected with HBV. The …

[PDF][PDF] an den, Groningen, MCCV,… Baan, CC (2023)

DM Hullegie-Peelen, HT Mora… - … specific TRM cells … - scholarlypublications …
Tissue-resident lymphocytes (TRLs) are noncirculating lymphocytes found in nonlymphoid
tissues, including the kidneys (1–3). Under physiological conditions, TRLs are key players in …