[HTML][HTML] Meiosis: dances between homologs

D Zickler, N Kleckner - Annual Review of Genetics, 2023 - annualreviews.org
The raison d'être of meiosis is shuffling of genetic information via Mendelian segregation
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …

The divergence of mutation rates and spectra across the Tree of Life

M Lynch, F Ali, T Lin, Y Wang, J Ni, H Long - EMBO reports, 2023 - embopress.org
Owing to advances in genome sequencing, genome stability has become one of the most
scrutinized cellular traits across the Tree of Life. Despite its centrality to all things biological …

[HTML][HTML] Evolution of the germline mutation rate across vertebrates

LA Bergeron, S Besenbacher, J Zheng, P Li… - Nature, 2023 - nature.com
The germline mutation rate determines the pace of genome evolution and is an evolving
parameter itself. However, little is known about what determines its evolution, as most …

A global catalog of whole-genome diversity from 233 primate species

LFK Kuderna, H Gao, MC Janiak, M Kuhlwilm, JD Orkin… - Science, 2023 - science.org
The rich diversity of morphology and behavior displayed across primate species provides an
informative context in which to study the impact of genomic diversity on fundamental …

The critically endangered vaquita is not doomed to extinction by inbreeding depression

JA Robinson, CC Kyriazis, SF Nigenda-Morales… - Science, 2022 - science.org
In cases of severe wildlife population decline, a key question is whether recovery efforts will
be impeded by genetic factors, such as inbreeding depression. Decades of excess mortality …

The Mutationathon highlights the importance of reaching standardization in estimates of pedigree-based germline mutation rates

LA Bergeron, S Besenbacher, T Turner, CJ Versoza… - Elife, 2022 - elifesciences.org
In the past decade, several studies have estimated the human per-generation germline
mutation rate using large pedigrees. More recently, estimates for various nonhuman species …

Selection against admixture and gene regulatory divergence in a long-term primate field study

TP Vilgalys, AS Fogel, JA Anderson, RS Mututua… - Science, 2022 - science.org
Genetic admixture is central to primate evolution. We combined 50 years of field
observations of immigration and group demography with genomic data from~ 9 generations …

Experimental estimates of germline mutation rate in eukaryotes: a phylogenetic meta-analysis

Y Wang, DJ Obbard - Evolution Letters, 2023 - academic.oup.com
Mutation is the ultimate source of all genetic variation, and over the last 10 years the ready
availability of whole-genome sequencing has permitted direct estimation of mutation rate for …

Temperature dependence of spontaneous mutation rates

AM Waldvogel, M Pfenninger - Genome Research, 2021 - genome.cshlp.org
Mutation is the source of genetic variation and the fundament of evolution. Temperature has
long been suggested to have a direct impact on realized spontaneous mutation rates. If …

Genomic signatures of high-altitude adaptation and chromosomal polymorphism in geladas

KL Chiou, MC Janiak, IA Schneider-Crease… - Nature ecology & …, 2022 - nature.com
Primates have adapted to numerous environments and lifestyles but very few species are
native to high elevations. Here we investigated high-altitude adaptations in the gelada …