[HTML][HTML] Meiosis: dances between homologs
D Zickler, N Kleckner - Annual Review of Genetics, 2023 - annualreviews.org
The raison d'être of meiosis is shuffling of genetic information via Mendelian segregation
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …
The divergence of mutation rates and spectra across the Tree of Life
Owing to advances in genome sequencing, genome stability has become one of the most
scrutinized cellular traits across the Tree of Life. Despite its centrality to all things biological …
scrutinized cellular traits across the Tree of Life. Despite its centrality to all things biological …
[HTML][HTML] Evolution of the germline mutation rate across vertebrates
LA Bergeron, S Besenbacher, J Zheng, P Li… - Nature, 2023 - nature.com
The germline mutation rate determines the pace of genome evolution and is an evolving
parameter itself. However, little is known about what determines its evolution, as most …
parameter itself. However, little is known about what determines its evolution, as most …
A global catalog of whole-genome diversity from 233 primate species
The rich diversity of morphology and behavior displayed across primate species provides an
informative context in which to study the impact of genomic diversity on fundamental …
informative context in which to study the impact of genomic diversity on fundamental …
The critically endangered vaquita is not doomed to extinction by inbreeding depression
In cases of severe wildlife population decline, a key question is whether recovery efforts will
be impeded by genetic factors, such as inbreeding depression. Decades of excess mortality …
be impeded by genetic factors, such as inbreeding depression. Decades of excess mortality …
The Mutationathon highlights the importance of reaching standardization in estimates of pedigree-based germline mutation rates
In the past decade, several studies have estimated the human per-generation germline
mutation rate using large pedigrees. More recently, estimates for various nonhuman species …
mutation rate using large pedigrees. More recently, estimates for various nonhuman species …
Selection against admixture and gene regulatory divergence in a long-term primate field study
Genetic admixture is central to primate evolution. We combined 50 years of field
observations of immigration and group demography with genomic data from~ 9 generations …
observations of immigration and group demography with genomic data from~ 9 generations …
Experimental estimates of germline mutation rate in eukaryotes: a phylogenetic meta-analysis
Mutation is the ultimate source of all genetic variation, and over the last 10 years the ready
availability of whole-genome sequencing has permitted direct estimation of mutation rate for …
availability of whole-genome sequencing has permitted direct estimation of mutation rate for …
Temperature dependence of spontaneous mutation rates
AM Waldvogel, M Pfenninger - Genome Research, 2021 - genome.cshlp.org
Mutation is the source of genetic variation and the fundament of evolution. Temperature has
long been suggested to have a direct impact on realized spontaneous mutation rates. If …
long been suggested to have a direct impact on realized spontaneous mutation rates. If …
Genomic signatures of high-altitude adaptation and chromosomal polymorphism in geladas
Primates have adapted to numerous environments and lifestyles but very few species are
native to high elevations. Here we investigated high-altitude adaptations in the gelada …
native to high elevations. Here we investigated high-altitude adaptations in the gelada …