[HTML][HTML] Anti-epileptogenic effects of antiepileptic drugs
B Miziak, A Konarzewska, M Ułamek-Kozioł… - International journal of …, 2020 - mdpi.com
Generally, the prevalence of epilepsy does not exceed 0.9% of the population and
approximately 70% of epilepsy patients may be adequately controlled with antiepileptic …
approximately 70% of epilepsy patients may be adequately controlled with antiepileptic …
Hippocampal pathophysiology: commonality shared by temporal lobe epilepsy and psychiatric disorders
S Nakahara, M Adachi, H Ito, M Matsumoto… - Neuroscience …, 2018 - Wiley Online Library
Accumulating evidence points to the association of epilepsy, particularly, temporal lobe
epilepsy (TLE), with psychiatric disorders, such as schizophrenia. Among these illnesses …
epilepsy (TLE), with psychiatric disorders, such as schizophrenia. Among these illnesses …
[HTML][HTML] Resveratrol for easing status epilepticus induced brain injury, inflammation, epileptogenesis, and cognitive and memory dysfunction—are we there yet?
Status epilepticus (SE) is a medical emergency exemplified by self-sustaining, unceasing
seizures or swiftly recurring seizure events with no recovery between seizures. The early …
seizures or swiftly recurring seizure events with no recovery between seizures. The early …
[HTML][HTML] Selected molecular targets for antiepileptogenesis
MJ Pawlik, B Miziak, A Walczak… - International Journal of …, 2021 - mdpi.com
The term epileptogenesis defines the usually durable process of converting normal brain
into an epileptic one. The resistance of a significant proportion of patients with epilepsy to …
into an epileptic one. The resistance of a significant proportion of patients with epilepsy to …
[HTML][HTML] VEGF modulates neurogenesis and microvascular remodeling in epileptogenesis after status epilepticus in immature rats
W Han, L Jiang, X Song, T Li, H Chen… - Frontiers in …, 2021 - frontiersin.org
Neurogenesis and angiogenesis are widely recognized to occur during epileptogenesis and
important in brain development. Because vascular endothelial growth factor (VEGF) is a …
important in brain development. Because vascular endothelial growth factor (VEGF) is a …
[HTML][HTML] Microglia modulate the structure and function of the hippocampus after early-life seizures
The hippocampus is a brain region well-known to exhibit structural and functional changes
in temporal lobe epilepsy. Studies analyzing the brains of patients with epilepsy and those …
in temporal lobe epilepsy. Studies analyzing the brains of patients with epilepsy and those …
Prospects of cannabidiol for easing status epilepticus-induced epileptogenesis and related comorbidities
The hippocampus is one of the most susceptible regions in the brain to be distraught with
status epilepticus (SE) induced injury. SE can occur from numerous causes and is more …
status epilepticus (SE) induced injury. SE can occur from numerous causes and is more …
[HTML][HTML] Antiseizure effects of Lilii Bulbus on pentylenetetrazol kindling-induced seizures in mice: Involvement of Reelin, Netrin-1, and semaphorin
HR Park, M Cai - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Abstract Lilii Bulbus (Lilium lancifolium Thunberg) has a proneurogenic effect on the
hippocampus. However, its effects on epilepsy and associated pathological features remain …
hippocampus. However, its effects on epilepsy and associated pathological features remain …
Upregulation of SLITRK5 in patients with epilepsy and in a rat model
Y Liu, L Zhang, M Ai, D Xia, H Chen, R Pang, R Mei… - Synapse, 2023 - Wiley Online Library
SLIT and NTRK‐like protein‐5 (SLITRK5) is one of the six members of SLITRK protein
family, which is widely expressed in central nervous system (CNS). In brain, SLITRK5 plays …
family, which is widely expressed in central nervous system (CNS). In brain, SLITRK5 plays …
The effects of calcineurin inhibitor FK506 on actin cytoskeleton, neuronal survival and glial reactions after pilocarpine-induced status epilepticus in mice
TQ Xiong, LM Chen, BH Tan, CY Guo, YN Li… - Epilepsy Research, 2018 - Elsevier
After status epilepticus (SE), actin cytoskeleton (F-actin) becomes progressively
deconstructed in the hippocampus, which is consistent with the delayed pyramidal cell death …
deconstructed in the hippocampus, which is consistent with the delayed pyramidal cell death …