Genetics and epigenetics of primary Sjögren syndrome: implications for future therapies

GE Thorlacius, A Björk… - Nature Reviews …, 2023 - nature.com
In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …

Epidemiology of Sjögren syndrome

M Beydon, S McCoy, Y Nguyen, T Sumida… - Nature Reviews …, 2024 - nature.com
Sjögren syndrome is a phenotypically varied autoimmune disorder that can occur alone in
primary Sjögren syndrome or in association with other connective tissue diseases (CTDs) …

Sjögren's syndrome

F André, BC Böckle - JDDG: Journal der Deutschen …, 2022 - Wiley Online Library
Sjögren's syndrome (SjS) is an autoimmune disease characterized by the triad of sicca
symptoms, fatigue and pain. This diagnosis is usually made in women at the average age of …

Interstitial lung disease and pulmonary damage in primary sjögren's syndrome: a systematic review and meta-analysis

O Berardicurti, A Marino, I Genovali, L Navarini… - Journal of Clinical …, 2023 - mdpi.com
Background: Pulmonary lung involvement is the most common extra-glandular manifestation
in patients with primary Sjögren's syndrome (pSS), leading to a worsening of the patient's …

Influence of the age at diagnosis in the disease expression of primary Sjögren syndrome. Analysis of 12,753 patients from the Sjögren Big Data Consortium

S Retamozo, N Acar-Denizli, IF Horváth… - Clinical and …, 2021 - discovery.ucl.ac.uk
OBJECTIVE: To analyse how the main components of the disease phenotype (sicca
symptoms, diagnostic tests, immunological markers and systemic disease) can be driven by …

Childhood-onset of primary Sjögren's syndrome: phenotypic characterization at diagnosis of 158 children

M Ramos-Casals, N Acar-Denizli, A Vissink… - …, 2021 - academic.oup.com
Objectives To characterize the phenotypic presentation at diagnosis of childhood-onset
primary SS. Methods The Big Data Sjögren Project Consortium is an international …

The spectrum of extraglandular manifestations in primary sjögren's syndrome

A Mihai, C Caruntu, C Jurcut, FC Blajut… - Journal of Personalized …, 2023 - mdpi.com
Extraglandular manifestations (EGMs) in primary Sjogren's syndrome (pSS) represent the
clinical expression of the systemic involvement in this disease. EGMs are characterized by a …

Sjögren syndrome: looking forward to the future

S Zandonella Callegher, I Giovannini… - Therapeutic …, 2022 - journals.sagepub.com
Primary Sjögren's syndrome (pSS) is a heterogeneous disease characterised by a wide
spectrum of manifestations that vary according to the different stages of the disease and …

Ten years of the ESSDAI: is it fit for purpose?

L de Wolff, S Arends, JF van Nimwegen… - Clinical and …, 2020 - research.rug.nl
Primary Sjögren's syndrome (pSS) is a very heterogeneous disease with systemic
manifestations such as arthritis, skin, lung and renal involvement. To be able to assess …

[PDF][PDF] One year in review 2021: Sjögren's syndrome

G Cafaro, R Bursi, LG Chatzis, G Fulvio… - Clin Exp …, 2021 - clinexprheumatol.org
Sjögren's syndrome (SS) is a multifactorial systemic autoimmune disease of unknown
aetiology characterised by a wide spectrum of different clinical manifestations and scattered …