ADVANCES IN ALZHEIMER'S DISEASE: A MULTIFACETED REVIEW OF POTENTIAL THERAPIES AND DIAGNOSTIC TECHNIQUES FOR EARLY DETECTION

M Sharma, P Pal, SK Gupta - Neurochemistry International, 2024 - Elsevier
Alzheimer's disease (AD) remains one of the most formidable neurological disorders,
affecting millions globally. This review provides a holistic overview of the therapeutic …

[HTML][HTML] Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases

Y Liang, X Sun, C Duan, S Tang, J Chen - Stem Cell Research & Therapy, 2023 - Springer
Inherited retinal diseases (IRDs) can induce severe sight-threatening retinal degeneration
and impose a considerable economic burden on patients and society, making efforts to cure …

New Perspectives in Stem Cell Transplantation and Associated Therapies to Treat Retinal Diseases: From Gene Editing to 3D Bioprinting

G Bovi dos Santos, TH de Lima-Vasconcellos… - Stem Cell Reviews and …, 2024 - Springer
Inherited and non-inherited retinopathies can affect distinct cell types, leading to progressive
cell death and visual loss. In the last years, new approaches have indicated exciting …

[HTML][HTML] Parkinson's Disease: What Can Retinal Imaging Tell Us?

M Di Pippo, S d'Agostino, F Ruggeri… - Journal of Integrative …, 2024 - imrpress.com
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor symptoms
such as tremors, rigidity, and bradykinesia. While the diagnosis of PD primarily relies on …

[HTML][HTML] Neurodegenerative Diseases: Molecular Mechanisms and Therapies

ZD Zhou, AH Kihara - International Journal of Molecular Sciences, 2023 - mdpi.com
Neurodegenerative diseases are characterized by the progressive degeneration or death of
neurons in the central or peripheral nervous system. Genetic, environmental, and lifestyle …

[HTML][HTML] Bridging Retinal and Cerebral Neurodegeneration: A Focus on Crosslinks between Alzheimer–Perusini's Disease and Retinal Dystrophies

L Donato, D Mordà, C Scimone, S Alibrandi… - Biomedicines, 2023 - mdpi.com
In the early stages of Alzheimer–Perusini's disease (AD), individuals often experience vision-
related issues such as color vision impairment, reduced contrast sensitivity, and visual acuity …

[HTML][HTML] Spatial Transcriptomic Analysis Reveals Regional Transcript Changes in Early and Late Stages of rd1 Model Mice with Retinitis Pigmentosa

Y Zhou, Y Sheng, M Pan, J Tu, X Zhao, Q Ge… - International Journal of …, 2023 - mdpi.com
Retinitis pigmentosa (RP) is the leading cause of inherited blindness with a genetically
heterogeneous disorder. Currently, there is no effective treatment that can protect vision for …

Stem cell therapy in retinal diseases: current evidence

L Rubinato, E Redolfi de Zan, V Sarao… - Expert Review of …, 2024 - Taylor & Francis
Introduction Retinal disorders, including age-related macular degeneration, diabetic
retinopathy, retinitis pigmentosa, and Stargardt disease, significantly impact vision and …

Biocompatibility evaluation of the novel organic semiconductors for the development of retinal prostheses/Author Ana Cetkovic

A Cetkovic - 2023 - epub.jku.at
Increase in global population has, as a consequence, a constant rise in number of patients
diagnosed with retinal degenerative diseases characterized by visual impairment and even …

Deconstructing organs: From decellularized organs, and stem cells niche to constructed organoids and engineering new organs

RR Resende - Seminars in cell & developmental biology, 2023 - pubmed.ncbi.nlm.nih.gov
Deconstructing organs: From decellularized organs, and stem cells niche to constructed
organoids and engineering new organs Deconstructing organs: From decellularized organs, and …