[HTML][HTML] Routine omics collection is a golden opportunity for European human research in space and analog environments

H Cope, CRG Willis, MJ MacKay, LA Rutter, LS Toh… - Patterns, 2022 - cell.com
Widespread generation and analysis of omics data have revolutionized molecular medicine
on Earth, yet its power to yield new mechanistic insights and improve occupational health …

Proteomics for biomarker discovery for diagnosis and prognosis of kidney transplantation rejection

LM Ramalhete, R Araújo, A Ferreira, CRC Calado - Proteomes, 2022 - mdpi.com
Renal transplantation is currently the treatment of choice for end-stage kidney disease,
enabling a quality of life superior to dialysis. Despite this, all transplanted patients are at risk …

HBFP: a new repository for human body fluid proteome

D Shao, L Huang, Y Wang, X Cui, Y Li, Y Wang… - Database, 2021 - academic.oup.com
Body fluid proteome has been intensively studied as a primary source for disease biomarker
discovery. Using advanced proteomics technologies, early research success has resulted in …

A multiplexed urinary biomarker panel has potential for Alzheimer's disease diagnosis using targeted proteomics and machine learning

J Hällqvist, RC Pinto, WE Heywood, J Cordey… - International Journal of …, 2023 - mdpi.com
As disease-modifying therapies are now available for Alzheimer's disease (AD), accessible,
accurate and affordable biomarkers to support diagnosis are urgently needed. We sought to …

Urinary metabolic biomarker profiling for cancer diagnosis by terahertz spectroscopy: Review and perspective

A Abina, T Korošec, U Puc, M Jazbinšek, A Zidanšek - Photonics, 2023 - mdpi.com
In the last decade, terahertz (THz) technologies have been introduced to the detection,
identification, and quantification of biomolecules in various biological samples. This review …

[HTML][HTML] Unveiling the Dichotomy of Urinary Proteins: Diagnostic Insights into Breast and Prostate Cancer and Their Roles

Y Feng, Q Huo, BY Li, H Yokota - Proteomes, 2024 - mdpi.com
This review covers the diagnostic potential of urinary biomarkers, shedding light on their
linkage to cancer progression. Urinary biomarkers offer non-invasive avenues for detecting …

Urinary biomarkers for amyotrophic lateral sclerosis: candidates, opportunities and considerations

ML Rogers, DW Schultz, V Karnaros… - Brain …, 2023 - academic.oup.com
Amyotrophic lateral sclerosis is a relentless neurodegenerative disease that is mostly fatal
within 3–5 years and is diagnosed on evidence of progressive upper and lower motor …

De-obstruction of bladder outlet in humans reverses organ remodelling by normalizing the expression of key transcription factors

A Akshay, AH Gheinani, M Besic, S Braga, AC Uldry… - BMC urology, 2024 - Springer
Background Benign prostatic hyperplasia in elderly males often causes bladder outlet
obstruction termed benign prostatic obstruction (BPO). BPO induces lower urinary tract …

Recent progress in mass spectrometry-based urinary proteomics

N Joshi, K Garapati, V Ghose, RK Kandasamy… - Clinical Proteomics, 2024 - Springer
Serum or plasma is frequently utilized in biomedical research; however, its application is
impeded by the requirement for invasive sample collection. The non-invasive nature of urine …

Targeted protein quantitation in human body fluids by mass spectrometry

YT Chen, WR Liao, HT Wang… - Mass spectrometry …, 2023 - Wiley Online Library
Human body fluids (biofluids) contain various proteins, some of which reflect individuals'
physiological conditions or predict diseases. Therefore, the analysis of biofluids can provide …