Bridging clinic and wildlife care with AI-powered pan-species computational pathology

K AbdulJabbar, SP Castillo, K Hughes… - Nature …, 2023 - nature.com
Cancers occur across species. Understanding what is consistent and varies across species
can provide new insights into cancer initiation and evolution, with significant implications for …

Rethinking antigen source: cancer vaccines based on whole tumor cell/tissue lysate or whole tumor cell

L Diao, M Liu - Advanced Science, 2023 - Wiley Online Library
Cancer immunotherapies have improved human health, and one among the important
technologies for cancer immunotherapy is cancer vaccine. Antigens are the most important …

[HTML][HTML] Preclinical studies performed in appropriate models could help identify optimal timing of combined chemotherapy and immunotherapy

Y Berckmans, J Ceusters, A Vankerckhoven… - Frontiers in …, 2023 - frontiersin.org
Immune checkpoint inhibitors (ICI) have been revolutionary in the field of cancer therapy.
However, their success is limited to specific indications and cancer types. Recently, the …

CanISO: a database of genomic and transcriptomic variations in domestic dog (Canis lupus familiaris)

IS Yang, I Jang, JO Yang, J Choi, MS Kim, KK Kim… - BMC genomics, 2023 - Springer
Abstract Background The domestic dog, Canis lupus familiaris, is a companion animal for
humans as well as an animal model in cancer research due to similar spontaneous …

Exploring the Tumor-Associated Risk of Mesenchymal Stem Cell Therapy in Veterinary Medicine

S Jeung, S Kim, J Ah, S Seo, U Jan, H Lee, JI Lee - Animals, 2024 - mdpi.com
Simple Summary This report discusses the ongoing research on, and concerns regarding,
the tumor promotion associated with multipotent stem cells, with a focus on mesenchymal …

A Phase 2, Single-Arm, Open-Label Clinical Trial on Adjuvant Peptide-Based Vaccination in Dogs with Aggressive Hemangiosarcoma Undergoing Surgery and …

L Marconato, L Tiraboschi, M Aralla, S Sabattini… - Cancers, 2023 - mdpi.com
Simple Summary Canine hemangiosarcoma shares many clinical, histologic and molecular
features with human angiosarcoma. Thus, the dog represents a powerful and alternative …

Molecular differences in mitochondrial genomes (mitogenomes) of dogs with recurrent and multiple tumours and their reference to the human mitochondrial genome

K Kowal, A Tkaczyk-Wlizło, J Gawor… - Annals of Animal …, 2024 - sciendo.com
The aim of this study was to identify molecular defects caused by mutations in mitochondrial
DNA in cases of recurrent and multiple canine tumours. We presented molecular differences …

AI-powered pan-species computational pathology: Bridging clinic and wildlife care

K AbdulJabbar, SP Castillo, K Hughes, H Davidson… - bioRxiv, 2022 - biorxiv.org
Cancers occur across species. Understanding what is consistent and varies across species
can provide new insights into cancer initiation and evolution, with significant implications for …

The Integration of Community-Dwelling Non-Human Companion Animals in Research Programs: A Scoping Review

M Medrano, LF Carver - One Health Innovation, 2024 - ojs.library.queensu.ca
Traditional purpose-bred laboratory animals used in clinical research and testing often do
not represent human conditions, with efficacy results often not replicated in human clinical …

Desenvolvimento de aplicativo móvel sobre medicamentos oncológicos veterinários para cães e gatos

KS ALMEIDA, VS MAGALHÃES… - Revista Brasileira de …, 2024 - rbfhss.org.br
Objective: This study aims to develop of a mobile application focusing on drugs used in
veterinary oncology targeted at dogs and cats. Methods: A technological production through …