Background Deprescribing can reduce the use of inappropriate or unnecessary medication;
however, the economic value of such interventions is uncertain. Objective This study seeks …

Purpose To conduct a systematic review of the economic impact of interventions intended at
optimizing medication use in older adults with multimorbidity and polypharmacy. Methods …

Objectives To investigate the extent to which articles of economic evaluations of healthcare
interventions indexed in MEDLINE incorporate research practices that promote …

Deprescribing involves reducing or stopping medications that are causing more harm than
good or are no longer needed. It is an important approach to managing polypharmacy, yet …

OBJECTIVES Older adults are often prescribed potentially inappropriate medications
associated with adverse health outcomes and increased health services utilization …

Prescription of potentially inappropriate medication (PIM) in older adults is associated with
poor clinical outcomes. The EU (7)-PIM list was created for the European market to improve …

Background Sedative use in older adults increases the risk of falls, fractures, and
hospitalizations. The D-PRESCRIBE (Developing Pharmacist-Led Research to Educate and …

OBJECTIVE To assess the agreement of several different measures of potentially
inappropriate prescribing (PIP) in older people and compare their relationship with patient …

Objectives To describe the distribution of costs based on potentially inappropriate
prescribing (PIP) and adverse drug reaction (ADR) status in terms of total direct costs and …

Purpose We discuss the known age-associated changes in drug metabolism and
elimination, the potential use of this information when selecting specific therapeutic …