Antimicrobial resistance is increasing despite new treatments being employed. With a
decrease in the discovery rate of novel antibiotics, this threatens to take humankind back to …

One of the global burdens of health care is an alcohol-associated liver disease (ALD) and
liver-related death which is caused due to acute or chronic consumption of alcohol. Chronic …

The human body is colonized by a large number of microbes coexisting peacefully with their
host. The most colonized site is the gastrointestinal tract (GIT). More than 70% of all the …

The therapeutic potential of phages has been considered since their first identification more
than a century ago. The evident concept of using a natural predator to treat bacterial …

Urinary tract infections (UTIs) are among the most common bacterial infectious diseases
encountered in clinical practice and account for significant morbidity and high medical costs …

There is growing concern about the emergence of bacterial strains showing resistance to all
classes of antibiotics commonly used in human medicine. Despite the broad range of …

Background. Treatment guidelines recommend stopping all implicated antibiotics at the
onset of Clostridium difficile infection (CDI), but many individuals have persistent or new …

Background Antibiotic-induced gut dysbiosis has been associated with colorectal cancer
(CRC) in older adults. This study will investigate whether an association exists between …

Objective Gut microbiota alterations are associated with obesity. Early exposure to
medications, including acid suppressants and antibiotics, can alter gut biota and may …

The design, synthesis, and characterization of enterobactin–antibiotic conjugates, hereafter
Ent-Amp/Amx, where the β-lactam antibiotics ampicillin (Amp) and amoxicillin (Amx) are …