Cell polarity in yeast
J Chiou, MK Balasubramanian… - Annual review of cell and …, 2017 - annualreviews.org
A conserved molecular machinery centered on the Cdc42 GTPase regulates cell polarity in
diverse organisms. Here we review findings from budding and fission yeasts that reveal both …
diverse organisms. Here we review findings from budding and fission yeasts that reveal both …
Rho GTPases: regulation of cell polarity and growth in yeasts
Eukaryotic cells display a wide range of morphologies important for cellular function and
development. A particular cell shape is made via the generation of asymmetry in the …
development. A particular cell shape is made via the generation of asymmetry in the …
Oscillatory dynamics of Cdc42 GTPase in the control of polarized growth
Cells promote polarized growth by activation of Rho-family protein Cdc42 at the cell
membrane. We combined experiments and modeling to study bipolar growth initiation in …
membrane. We combined experiments and modeling to study bipolar growth initiation in …
Cell polarization in budding and fission yeasts
SG Martin, RA Arkowitz - FEMS microbiology reviews, 2014 - academic.oup.com
Polarization is a fundamental cellular property, which is essential for the function of
numerous cell types. Over the past three to four decades, research using the best …
numerous cell types. Over the past three to four decades, research using the best …
Spontaneous Cdc42 polarization independent of GDI-mediated extraction and actin-based trafficking
FO Bendezú, V Vincenzetti, D Vavylonis, R Wyss… - PLoS …, 2015 - journals.plos.org
The small Rho-family GTPase Cdc42 is critical for cell polarization and polarizes
spontaneously in absence of upstream spatial cues. Spontaneous polarization is thought to …
spontaneously in absence of upstream spatial cues. Spontaneous polarization is thought to …
Shaping fission yeast with microtubules
F Chang, SG Martin - Cold Spring Harbor perspectives …, 2009 - cshperspectives.cshlp.org
For cell morphogenesis, the cell must establish distinct spatial domains at specified
locations at the cell surface. Here, we review the molecular mechanisms of cell polarity in …
locations at the cell surface. Here, we review the molecular mechanisms of cell polarity in …
Optogenetics reveals Cdc42 local activation by scaffold-mediated positive feedback and Ras GTPase
I Lamas, L Merlini, A Vještica, V Vincenzetti… - PLoS …, 2020 - journals.plos.org
Local activity of the small GTPase Cdc42 is critical for cell polarization. Whereas scaffold-
mediated positive feedback was proposed to break symmetry of budding yeast cells and …
mediated positive feedback was proposed to break symmetry of budding yeast cells and …
[PDF][PDF] Chaperone-facilitated aggregation of thermo-sensitive proteins shields them from degradation during heat stress
Cells have developed protein quality-control strategies to manage the accumulation of
misfolded substrates during heat stress. Using a soluble reporter of misfolding in fission …
misfolded substrates during heat stress. Using a soluble reporter of misfolding in fission …
A Ras1‐Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans
CB Nichols, ZH Perfect, JA Alspaugh - Molecular microbiology, 2007 - Wiley Online Library
Pathogenic microorganisms must precisely regulate morphogenesis to survive and
proliferate within an infected host. This regulation is often controlled by conserved signal …
proliferate within an infected host. This regulation is often controlled by conserved signal …
Fission yeast Pak1 phosphorylates anillin-like Mid1 for spatial control of cytokinesis
JO Magliozzi, J Sears, L Cressey, M Brady… - Journal of Cell …, 2020 - rupress.org
Protein kinases direct polarized growth by regulating the cytoskeleton in time and space and
could play similar roles in cell division. We found that the Cdc42-activated polarity kinase …
could play similar roles in cell division. We found that the Cdc42-activated polarity kinase …