Bacillus spore-based oral carriers loading curcumin for the therapy of colon cancer

L Yin, Z Meng, Y Zhang, K Hu, W Chen, K Han… - Journal of Controlled …, 2018 - Elsevier
Oral drug delivery has attracted substantial attention due to its advantages over other
administration routes. Bacillus spores, as oral probiotic agents, are applied widely. In this …

Nanostructured liquid-crystalline particles for drug delivery

A Lancelot, T Sierra, JL Serrano - Expert Opinion on Drug Delivery, 2014 - Taylor & Francis
Introduction: Nanostructured lyotropic liquid crystal particles (LLC NPs) have proven to be
extremely useful tools for applications in drug delivery. These structured nanoparticles are …

Tocophersolan stabilized lipid nanocapsules with high drug loading to improve the permeability and oral bioavailability of curcumin

P Bapat, R Ghadi, D Chaudhari, SS Katiyar… - International journal of …, 2019 - Elsevier
The present investigation highlights the development of D-α-Tocopheryl polyethylene glycol
1000 succinate (Tocophersolan; TPGS) stabilized lipid nanocapsules for enhancing the oral …

Multiple nanoemulsion system for an oral combinational delivery of oxaliplatin and 5-fluorouracil: preparation and in vivo evaluation

R Pangeni, SW Choi, OC Jeon, Y Byun… - International journal of …, 2016 - Taylor & Francis
Oxaliplatin (OXA) is a third-generation cisplatin analog that has been approved as first-line
chemotherapy in combination with 5-fluorouracil (5-FU) for the treatment of resectable and …

Tyrosine kinase inhibitor conjugated quantum dots for non-small cell lung cancer (NSCLC) treatment

NS Kulkarni, V Parvathaneni, SK Shukla… - European Journal of …, 2019 - Elsevier
Non-small cell lung cancer is a major sub-type of lung cancer that is associated with a poor
diagnosis resulting in poor therapy for the disorder. In order to achieve a better prognosis …

Pazopanib-laden lipid based nanovesicular delivery with augmented oral bioavailability and therapeutic efficacy against non-small cell lung cancer

SJ Nadaf, SG Killedar, VM Kumbar, DA Bhagwat… - International Journal of …, 2022 - Elsevier
The present investigation deals with the pazopanib-loaded solid lipid nanoparticles (Pazo-
SLNs) and their in-vitro and in-vivo assessments. Quality by design approach employing the …

Recent advances in SN-38 drug delivery system

J Yang, L Jia, Z He, Y Wang - International Journal of Pharmaceutics, 2023 - Elsevier
DNA topoisomerase I plays a key role in lubricating the wheels of DNA replication or RNA
transcription through breaking and reconnecting DNA single-strand. It is widely known that …

Investigating the role of hyaluronic acid in improving curcumin bioaccessibility from nanoemulsions

A Aguilera-Garrido, T del Castillo-Santaella… - Food Chemistry, 2021 - Elsevier
A major challenge in delivering curcumin effectively to the gut is its low solubility. One
interesting approach to increase curcumin bioaccessibility is its emulsification. Here, we …

On the nanopore confinement of therapeutic drugs into mesoporous silica materials and its implications

E Juère, F Kleitz - Microporous and Mesoporous Materials, 2018 - Elsevier
This short review deals with the effects of confinement occurring when a therapeutic drug is
adsorbed inside the mesopores of silica materials and the implications it may have in the …

[HTML][HTML] Thiolated-polymer-based nanoparticles as an avant-garde approach for anticancer therapies—reviewing thiomers from chitosan and hyaluronic acid

R Grosso, MV de-Paz - Pharmaceutics, 2021 - mdpi.com
Thiomers (or thiolated polymers) have broken through as avant-garde approaches in
anticancer therapy. Their distinguished reactivity and properties, closely linked to their final …