Purpose The present work reports rationalized development and characterization of
solidified self-nanoemulsifying drug delivery system for oral delivery of combinatorial …

Purpose The present study explores the potential of bicontinous cubic liquid crystalline
nanoparticles (LCNPs) for improving therapeutic potential of doxorubicin. Methods …

Fabricating a nanocargo made from natural constituents for delivering the anticancer drug
curcumin orally may offer hope for cancer patients. In this study, protein and polysaccharides …

Breast cancer (BC) remains a significant health burden worldwide, necessitating the
development of innovative therapeutic strategies. The B-cell lymphoma 2 (Bcl-2) family …

Maslinic acid (MA) is a plant-derived, low water-soluble compound with antitumor activity.
We have formulated MA in the form of solid lipid nanoparticles (SLNs) with three different …

Abstract Exosomes are 40-to 100-nm membrane-bound small vesicles that carry a great
variety of cellular cargoes including proteins, DNA, messenger RNAs (mRNAs), and …

The oral route of administration for lipid-based nanocarriers is of immense importance for
the drugs having low bioavailability because of extensive first-pass metabolism. These drug …

Pro-apoptotic analogues of vitamin E (VE) exert selective anti-cancer effect on various
animal cancer models. Neither suitable formulation of α-tocopheryl succinate (α-TOS) …

There has been increasing interest in research and development of nanocrystals for the
delivery of poorly water-soluble drugs that can be directly produced from solution …

Introduction: P-glycoprotein (P-gp) is a multi-specific efflux transporter belonging to ATP-
binding cassette (ABC) transporter family, encoded by the ABCB1 gene, which significantly …