The development of highly funtional and orally available nanoparticles is the ultimate goal in
nanoparticle delivery. Various functional nanoparticles have been studied to that end but …

The prevention and treatment of lung metastasis of breast cancer remain a major challenge.
The vascular cell adhesion molecule-1 (VCAM-1) could provide a potential therapeutic …

The purpose of this study is to design a flower‐shaped lactose loaded curcumin solid lipid
nanoparticles dry powder inhaler and characterize it to improve the solubility and dissolution …

Our research aimed to enhance the oral bioavailability of doxorubicin hydrochloride (DOX·
HCl) while minimizing the potential for myocardial toxicity. To achieve this goal, we …

The rise of tuberculosis (TB) superbugs has impeded efforts to control this infectious ailment,
and new treatment options are few. Paradoxical Inflammation (PI) is another major problem …

Thermosensitive liposomes (TSL) have been used for localized temperature-responsive
release of chemotherapeutics into solid cancers, with a minimum of one invention currently …

Background Effective oral delivery of drugs remains a major challenge given their possible
undesirable physicochemical properties, physicochemical factors, and the physiological …

Oral chemotherapy can improve the life quality of patients; however, the therapeutic effects
are limited by low bioavailability and rapid in vivo elimination of anticancer drugs. Here, we …

A microfluidics approach to synthesize core–shell nanocarriers with high pH tunability is
described. The sacrificial shell protects the core layer with the drugs and prevents their …

Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that can change the
expression of downstream target genes by catalyzing the trimethylation of lysine 27 of …