Competing paradigms of obesity pathogenesis: energy balance versus carbohydrate-insulin models

DS Ludwig, CM Apovian, LJ Aronne, A Astrup… - European journal of …, 2022 - nature.com
The obesity pandemic continues unabated despite a persistent public health campaign to
decrease energy intake (“eat less”) and increase energy expenditure (“move more”). One …

[HTML][HTML] Ultraprocessed foods and obesity risk: a critical review of reported mechanisms

VM Valicente, CH Peng, KN Pacheco, L Lin, EI Kielb… - Advances in …, 2023 - Elsevier
Epidemiologic evidence supports a positive association between ultraprocessed food (UPF)
consumption and body mass index. This has led to recommendations to avoid UPFs despite …

Obesogens: a unifying theory for the global rise in obesity

JJ Heindel, RH Lustig, S Howard… - International Journal of …, 2024 - nature.com
Despite varied treatment, mitigation, and prevention efforts, the global prevalence and
severity of obesity continue to worsen. Here we propose a combined model of obesity, a …

Validation of Food Compass with a healthy diet, cardiometabolic health, and mortality among US adults, 1999–2018

M O'Hearn, J Erndt-Marino, S Gerber… - Nature …, 2022 - nature.com
Abstract The Food Compass is a nutrient profiling system (NPS) to characterize the
healthfulness of diverse foods, beverages and meals. In a nationally representative cohort of …

Carbohydrate-insulin model: does the conventional view of obesity reverse cause and effect?

DS Ludwig - … Transactions of the Royal Society B, 2023 - royalsocietypublishing.org
Conventional obesity treatment, based on the First Law of Thermodynamics, assumes that
excess body fat gain is driven by overeating, and that all calories are metabolically alike in …

Comprehensive assessment of chrononutrition behaviors among nationally representative adults: Insights from National Health and Nutrition Examination Survey …

S Farsijani, Z Mao, JA Cauley, AB Newman - Clinical Nutrition, 2023 - Elsevier
Background Aligning the time of food intake, ie, chrononutrition, with the body's circadian
clock can have a significant impact on overall health, particularly cardiometabolic health …

[HTML][HTML] Obesogens and obesity: State-of-the-science and future directions summary from a Healthy Environment and Endocrine Disruptors Strategies workshop

JJ Heindel, JA Alvarez, E Atlas, MC Cave… - The American Journal of …, 2023 - Elsevier
Abstract On September 7 and 8, 2022, Healthy Environment and Endocrine Disruptors
Strategies, an Environmental Health Sciences program, convened a scientific workshop of …

The age‐related obesity paradigm: results from two large prospective cohort studies

YZ Ge, T Liu, L Deng, Q Zhang, CA Liu… - Journal of Cachexia …, 2024 - Wiley Online Library
Background The obesity paradigm has been a health concern globally for many years, its
meaning is controversial. In this study, we assess the characteristics and causes of obesity …

[HTML][HTML] Evidence for the carbohydrate–insulin model in a reanalysis of the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) …

A Soto-Mota, MA Pereira, CB Ebbeling… - The American journal of …, 2023 - Elsevier
Abstract Background The Diet Intervention Examining The Factors Interacting with Treatment
Success (DIETFITS) trial demonstrated that meaningful weight loss can be achieved with …

Irvingia gabonensis baill.(African Mango): A comprehensive review of its ethnopharmacological significance, unveiling its long-standing history and therapeutic …

YR Hassan, RA El-Shiekh, HM El Hefnawy… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Irvingia gabonensis (Aubry-Lecomte ex O'Rorke)
Baill.(IG) is a multipurpose tree native to tropical Africa such as Equatorial Guinea, Nigeria …