This paper describes an action framework for countries with low tuberculosis (TB) incidence
(< 100 TB cases per million population) that are striving for TB elimination. The framework …

Despite the introduction 40 years ago of the inexpensive and effective four-drug (isoniazid,
rifampicin, pyrazinamide and ethambutol) treatment regimen, tuberculosis (TB) continues to …

Background China scaled up a tuberculosis control programme (based on the directly
observed treatment, short-course [DOTS] strategy) to cover half the population during the …

Bedaquiline, a diarylquinoline, improved cure rates when added to a multidrug-resistant
tuberculosis (MDR-TB) treatment regimen in a previous placebo-controlled, phase 2 trial …

Tuberculosis (TB) elimination and pre-elimination, with thresholds of 1 and 10 incident
cases per million population, respectively, were considered achievable for low TB incidence …

About 1· 3 million people died of tuberculosis in 2012, despite availability of effective drug
treatment. Barriers to improvements in outcomes include long treatment duration (resulting …

This paper describes an action framework for countries with low tuberculosis (TB) incidence
(< 100 TB cases per million population) that are striving for TB elimination. The framework …

The importance of adequately managing multidrug-resistant (MDR) and extensively drug-
resistant (XDR) tuberculosis (TB) cases for TB control and elimination are underlined in the …

Identifying latently infected individuals is crucial for the elimination of tuberculosis (TB). We
evaluated for the first time the performance of a new type of interferon-γ release assay …

Without better vaccines it is unlikely that tuberculosis (TB) will ever be eliminated. An
investment of∼€ 560 million is considered necessary to develop a new, effective vaccine in …