Increased Wnt5a/ROR2 signaling is associated with chondrogenesis in meniscal degeneration
Y Inoue, K Kumagai, K Ishikawa, I Kato… - Journal of …, 2024 - Wiley Online Library
The aim of the present study was to investigate the association between chondrogenic
differentiation and Wnt signal expression in the degenerative process of the human …
differentiation and Wnt signal expression in the degenerative process of the human …
Defining the extracellular matrix in non-cartilage soft tissues in osteoarthritis–a systematic review
Objective Osteoarthritis (OA) is increasingly seen as a disease of global joint dysfunction,
affecting not only cartilage but also the other joint tissues. Extracellular matrix (ECM) is a …
affecting not only cartilage but also the other joint tissues. Extracellular matrix (ECM) is a …
Is the mechanical function of meniscal tissue altered in osteoarthritic knees?
Background Deteriorating meniscal function is thought to play a role in knee osteoarthritis.
Meniscal proteoglycans maintain mechanical stiffness of the tissue through electrostatic …
Meniscal proteoglycans maintain mechanical stiffness of the tissue through electrostatic …
Targeted transcriptomic analyses of RNA isolated from formalin‐fixed and paraffin‐embedded human menisci
FA Monibi, T Pannellini, B Croen… - Journal of …, 2022 - Wiley Online Library
Formalin‐fixed and paraffin‐embedded (FFPE) biospecimens are a valuable and widely‐
available resource for diagnostic and research applications. With biobanks of tissue …
available resource for diagnostic and research applications. With biobanks of tissue …
Targeting IKK epsilon to Prevent Meniscal Degeneration in Osteoarthritis: Insights from Human Tissue and Mouse Models
R Hirose, Y Akasaki, M Kuwahara, T Uchida, Y Hyodo… - 2024 - researchsquare.com
Objective. Meniscal degeneration may precede or indicate early-stage osteoarthritis (OA);
however, the pathogenetic involvement of the NF-κB pathway and its upstream IκB kinase …
however, the pathogenetic involvement of the NF-κB pathway and its upstream IκB kinase …