The impact of pre-existing comorbidities and therapeutic interventions on COVID-19
LA Callender, M Curran, SM Bates… - Frontiers in …, 2020 - frontiersin.org
Evidence from the global outbreak of SARS-CoV-2 has clearly demonstrated that individuals
with pre-existing comorbidities are at a much greater risk of dying from COVID-19. This is of …
with pre-existing comorbidities are at a much greater risk of dying from COVID-19. This is of …
Manifestations of systemic diseases and conditions that affect the periodontal attachment apparatus: Case definitions and diagnostic considerations
JM Albandar, C Susin… - Journal of clinical …, 2018 - Wiley Online Library
Objectives This review proposes case definitions and diagnostic considerations of systemic
disorders and conditions that affect the periodontal attachment apparatus. Importance …
disorders and conditions that affect the periodontal attachment apparatus. Importance …
Severe obesity, increasing age and male sex are independently associated with worse in-hospital outcomes, and higher in-hospital mortality, in a cohort of patients …
Abstract Background & aims New York is the current epicenter of Coronavirus disease 2019
(COVID-19) pandemic. The underrepresented minorities, where the prevalence of obesity is …
(COVID-19) pandemic. The underrepresented minorities, where the prevalence of obesity is …
Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection
Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly
understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse …
understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse …
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
Up to 49% of certain types of cancer are attributed to obesity, and potential mechanisms
include overproduction of hormones, adipokines, and insulin. Cytotoxic immune cells …
include overproduction of hormones, adipokines, and insulin. Cytotoxic immune cells …
Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
The influence of the gut microbiome on host metabolism through the regulation of gut hormone release
The microbial community of the gut conveys significant benefits to host physiology. A clear
relationship has now been established between gut bacteria and host metabolism in which …
relationship has now been established between gut bacteria and host metabolism in which …
The association of periodontal diseases with metabolic syndrome and obesity
S Jepsen, J Suvan, J Deschner - Periodontology 2000, 2020 - Wiley Online Library
Periodontitis is a multifactorial chronic inflammatory disease associated with dysbiotic
plaque biofilms and characterized by progressive destruction of the toothsupporting …
plaque biofilms and characterized by progressive destruction of the toothsupporting …
Arachidonic acid metabolites in cardiovascular and metabolic diseases
T Sonnweber, A Pizzini, M Nairz, G Weiss… - International journal of …, 2018 - mdpi.com
Lipid and immune pathways are crucial in the pathophysiology of metabolic and
cardiovascular disease. Arachidonic acid (AA) and its derivatives link nutrient metabolism to …
cardiovascular disease. Arachidonic acid (AA) and its derivatives link nutrient metabolism to …
Obesity and type 2 diabetes mellitus drive immune dysfunction, infection development, and sepsis mortality
LM Frydrych, G Bian, DE O'Lone… - Journal of leukocyte …, 2018 - academic.oup.com
Obesity and type 2 diabetes mellitus (T2D) are global pandemics. Worldwide, the
prevalence of obesity has nearly tripled since 1975 and the prevalence of T2D has almost …
prevalence of obesity has nearly tripled since 1975 and the prevalence of T2D has almost …