Mesenchymal stromal cells (MSCs) are a subset of heterogeneous non-hematopoietic
fibroblast-like cells that can differentiate into cells of multiple lineages, such as …

Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents
may induce autoimmunity. It occurs when similarities between foreign and self-peptides …

Systemic lupus erythematosus (SLE), often considered the prototype of autoimmune
diseases, is characterized by over-activation of the autoimmune system with abnormal …

Introduction: Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that
accumulates in lysosomes where it inhibits some important functions by increasing the pH …

Acute systemic lupus erythematosus (SLE) courses with surges of antibody-secreting cells
(ASCs) whose origin, diversity and contribution to serum autoantibodies remain unknown …

Antibodies to DNA and chromatin drive autoimmunity in systemic lupus erythematosus
(SLE). Null mutations and hypomorphic variants of the secreted deoxyribonuclease …

The interaction over time of genetic, epigenetic and environmental factors (ie, autoimmune
ecology) increases or decreases the liability an individual would have to develop an …

Objectives The relationship of immune dysregulation and autoantibody production that may
contribute to systemic lupus erythematosus (SLE) pathogenesis is unknown. This study …

Telitacicept (Tai'ai®) is fusion protein comprising a recombinant transmembrane activator
and calcium modulator and cyclophilin ligand interactor (TACI) receptor fused to the …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder, characterized by
production of autoantibodies directed against nuclear and cytoplasmic antigens, which may …