Angiogenesis is one of the hallmarks of cancer. Several studies have shown that vascular
endothelium growth factor (VEGF) plays a leading role in angiogenesis progression …

Hepatocellular carcinoma (HCC) is the sixth most commonly malignant tumor and the third
leading cause of cancer-related death in the world, and the early diagnosis and treatment of …

Hepatectomy is a main therapeutic strategy for hepatocellular carcinoma (HCC), which
requires removal of primary and disseminated tumors and maximum preservation of normal …

Integrin α6 has been considered a promising biomarker, is overexpressed in many tumors,
and plays a vital role in tumor formation, recurrence, and metastasis. In this study, we …

Simple Summary Cancer cells often present a different set of proteins on their surface than
normal cells. This also applies to integrins, a class of 24 cell surface receptors which mainly …

Central nervous system leukemia (CNS-L) is caused by leukemic cells infiltrating into the
meninges or brain parenchyma and remains the main reason for disease relapse. Currently …

Objective Optical molecular imaging technology that indiscriminately detects intracranial
glioblastoma (GBM) can help neurosurgeons effectively remove tumor masses. Transferrin …

The molecular classification has been playing a crucial role in the precise theranostics of
cancer. Compared with the invasive biopsy, the in vivo noninvasive detection of biomarkers …

Introduction Integrin α6 is an attractive diagnostic biomarker for molecular imaging of
hepatocellular carcinoma (HCC) as it has an extremely high positive rate (approximately …

In this study, we reported a 99mTc-labeled integrin α6-targeted peptide as the molecular
imaging probe for tumor imaging by single-photon emission computed tomography …