Pulmonary surfactant is a lipid–protein complex, synthesized and secreted by the respiratory
epithelium of lungs to the alveolar spaces, whose main function is to reduce the surface …

Pulmonary surfactant is a lipid–protein complex that lines and stabilizes the respiratory
interface in the alveoli, allowing for gas exchange during the breathing cycle. At the same …

Reported associations between air pollution and pulmonary and cardiovascular diseases
prompted studies on the effects of gold nanoparticles (Au NP) on pulmonary surfactant …

The lives of thousands premature babies have been saved along the last thirty years thanks
to the establishment and consolidation of pulmonary surfactant replacement therapies …

Clinical pulmonary surfactant is routinely used to treat premature newborns with respiratory
distress syndrome, and has shown great potential in alleviating a number of neonatal and …

The alveolar type II epithelial (ATII) cell is highly specialised for the synthesis and storage, in
intracellular lamellar bodies, of phospholipid destined for secretion as pulmonary surfactant …

Acute lung injury and acute respiratory distress syndrome (ARDS) are characterised by
severe hypoxemic respiratory failure and poor lung compliance. Despite advances in clinical …

A molecular film of pulmonary surfactant strongly reduces the surface tension of the lung
epithelium–air interface. Human pulmonary surfactant contains 5–10% cholesterol by mass …

Pulmonary surfactant lowers surface tension in the lungs. Physiological studies indicate two
key aspects of this function: that the surfactant film forms rapidly; and that when compressed …

Lipid mediators are important in lung biochemistry and are derived from the enzymatic
oxidation of arachidonic and docosahexaenoic acids, which are PUFAs that are present in …