The molecular and clinical landscape of pancreatic neuroendocrine tumors

BDO Batukbhai, A De Jesus-Acosta - Pancreas, 2019 - journals.lww.com
Pancreatic neuroendocrine tumors are rare tumors of the pancreas originating from the islets
of the Langerhans. These tumors comprise 1% to 3% of all newly diagnosed pancreatic …

Inherent variability of cancer-specific aneuploidy generates metastases

M Bloomfield, P Duesberg - Molecular cytogenetics, 2016 - Springer
Background The genetic basis of metastasis is still unclear because metastases carry
individual karyotypes and phenotypes, rather than consistent mutations, and are rare …

Upregulation of INS-IGF2 read-through expression and identification of a novel INS-IGF2 splice variant in insulinomas

LE Johannessen, I Panagopoulos… - Oncology …, 2016 - spandidos-publications.com
Fusion transcripts arising from the combination of exons residing on neighboring genes on
the same chromosome may give rise to chimeric or novel proteins. Such read-through …

Transcriptomic profiling of tumor aggressiveness in sporadic nonfunctioning pancreatic neuroendocrine neoplasms

SP Haugvik, D Vodák, L Haugom, E Hovig… - Pancreas, 2016 - journals.lww.com
Objectives The aim of the study was to compare RNA sequencing data of sporadic
nonfunctioning pancreatic neuroendocrine neoplasms (PNENs) to identify gene expression …