[HTML][HTML] Cannabinoids, endocannabinoids, and synthetic cannabimimetic molecules in neuromuscular disorders
FA Iannotti - International Journal of Molecular Sciences, 2023 - mdpi.com
Neuromuscular disorders (NMDs) encompass a large heterogeneous group of hereditary
and acquired diseases primarily affecting motor neurons, peripheral nerves, and the skeletal …
and acquired diseases primarily affecting motor neurons, peripheral nerves, and the skeletal …
The emerging role of the endocannabinoidome-gut microbiome axis in eating disorders
HD Mir, G Giorgini, V Di Marzo - Psychoneuroendocrinology, 2023 - Elsevier
Among the sources of chemical signals regulating food intake, energy metabolism and body
weight, few have attracted recently as much attention as the expanded endocannabinoid …
weight, few have attracted recently as much attention as the expanded endocannabinoid …
When dysbiosis meets dystrophy: an unwanted gut‐muscle connection
A Jayaraman, S Pettersson - EMBO molecular medicine, 2023 - embopress.org
Duchenne muscular dystrophy (DMD) is a devastating neuromuscular degenerative disease
with no known cure to date. In recent years, the hypothesis of a “gut‐muscle axis” has …
with no known cure to date. In recent years, the hypothesis of a “gut‐muscle axis” has …
[HTML][HTML] Dysfunctional endocannabinoid CB1 receptor expression and signaling contribute to skeletal muscle cell toxicity induced by simvastatin
Statins are the most prescribed lipid-lowering agents worldwide. Their use is generally safe,
although muscular toxicity occurs in about 1 in 10.000 patients. In this study, we explored the …
although muscular toxicity occurs in about 1 in 10.000 patients. In this study, we explored the …
[HTML][HTML] Mitochondria and Reactive Oxygen Species: The Therapeutic Balance of Powers for Duchenne Muscular Dystrophy
SR Casati, D Cervia, P Roux-Biejat, C Moscheni… - Cells, 2024 - mdpi.com
Duchenne muscular dystrophy (DMD) is a genetic progressive muscle-wasting disorder that
leads to rapid loss of mobility and premature death. The absence of functional dystrophin in …
leads to rapid loss of mobility and premature death. The absence of functional dystrophin in …
[HTML][HTML] Polyamines and physical activity in musculoskeletal diseases: A potential therapeutic challenge
Autophagy dysregulation is commonplace in the pathogenesis of several invalidating
diseases, such as musculoskeletal diseases. Polyamines, as spermidine and spermine, are …
diseases, such as musculoskeletal diseases. Polyamines, as spermidine and spermine, are …
[HTML][HTML] The metabolomic plasma profile of patients with Duchenne muscular dystrophy: Providing new evidence for its pathogenesis
H Xu, X Cai, K Xu, Q Wu, B Xu - Orphanet Journal of Rare Diseases, 2023 - Springer
Background Duchenne muscular dystrophy (DMD) is a fatal genetic muscle-wasting disease
that affects 1 in 5000 male births with no current cure. Despite great progress has been …
that affects 1 in 5000 male births with no current cure. Despite great progress has been …
[HTML][HTML] Advancing Biomarker Discovery and Therapeutic Targets in Duchenne Muscular Dystrophy: A Comprehensive Review
M Molinaro, Y Torrente, C Villa, A Farini - International Journal of …, 2024 - mdpi.com
Mounting evidence underscores the intricate interplay between the immune system and
skeletal muscles in Duchenne muscular dystrophy (DMD), as well as during regular muscle …
skeletal muscles in Duchenne muscular dystrophy (DMD), as well as during regular muscle …
[HTML][HTML] Impact of gut microbiota on the peripheral nervous system in physiological, regenerative and pathological conditions
S Calabrò, S Kankowski, M Cescon… - International Journal of …, 2023 - mdpi.com
It has been widely demonstrated that the gut microbiota is responsible for essential functions
in human health and that its perturbation is implicated in the development and progression …
in human health and that its perturbation is implicated in the development and progression …
Dynamic changes in butyrate levels regulate satellite cell homeostasis by preventing spontaneous activation during aging
S Chen, L Huang, B Liu, H Duan, Z Li, Y Liu… - Science China Life …, 2024 - Springer
The gut microbiota plays a pivotal role in systemic metabolic processes and in particular
functions, such as developing and preserving the skeletal muscle system. However, the …
functions, such as developing and preserving the skeletal muscle system. However, the …