[HTML][HTML] An inflammation-centric view of neurological disease: beyond the neuron

SD Skaper, L Facci, M Zusso, P Giusti - Frontiers in cellular …, 2018 - frontiersin.org
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

[HTML][HTML] Neuroinflammation and oxidative stress in diabetic neuropathy: futuristic strategies based on these targets

R Sandireddy, VG Yerra, A Areti… - International journal of …, 2014 - hindawi.com
In Diabetes, the chronic hyperglycemia and associated complications affecting peripheral
nerves are one of the most commonly occurring microvascular complications with an overall …

Magnetic nanoparticles for theragnostics

VI Shubayev, TR Pisanic II, S Jin - Advanced drug delivery reviews, 2009 - Elsevier
Engineered magnetic nanoparticles (MNPs) represent a cutting-edge tool in medicine
because they can be simultaneously functionalized and guided by a magnetic field. Use of …

The neuropathic pain triad: neurons, immune cells and glia

J Scholz, CJ Woolf - Nature neuroscience, 2007 - nature.com
Nociceptive pain results from the detection of intense or noxious stimuli by specialized high-
threshold sensory neurons (nociceptors), a transfer of action potentials to the spinal cord …

Anti-inflammatory protein TSG-6 secreted by bone marrow mesenchymal stem cells attenuates neuropathic pain by inhibiting the TLR2/MyD88/NF-κB signaling …

H Yang, L Wu, H Deng, Y Chen, H Zhou, M Liu… - Journal of …, 2020 - Springer
Background Neuroinflammation plays a vital role in the development and maintenance of
neuropathic pain. Recent evidence has proved that bone marrow mesenchymal stem cells …

Hydrogen sulfide attenuates lipopolysaccharide‐induced inflammation by inhibition of p38 mitogen‐activated protein kinase in microglia

LF Hu, PTH Wong, PK Moore… - Journal of …, 2007 - Wiley Online Library
The present study attempts to investigate the effect of H2S on lipopolysaccharide (LPS)‐
induced inflammation in both primary cultured microglia and immortalized murine BV‐2 …

Differential expression of cytokines in painful and painless neuropathies

N Uceyler, JP Rogausch, KV Toyka, C Sommer - Neurology, 2007 - AAN Enterprises
Background: Pain is a common symptom in peripheral neuropathies. The factors
determining why some peripheral neuropathies are painful and others are not are …

Wallerian degeneration and peripheral nerve conditions for both axonal regeneration and neuropathic pain induction

P Dubový - Annals of Anatomy-Anatomischer Anzeiger, 2011 - Elsevier
Wallerian degeneration is a cascade of stereotypical events in reaction to injury of nerve
fibres. These events consist of cellular and molecular alterations, including macrophage …

[HTML][HTML] Towards an effective and safe treatment of inflammatory pain: a Delphi-guided expert consensus

G Varrassi, E Alon, M Bagnasco, L Lanata… - Advances in …, 2019 - Springer
Objective The clinical management of inflammatory pain requires an optimal balance
between effective analgesia and associated safety risks. To date, mechanisms associated …

Role of miRNAs in diabetic neuropathy: mechanisms and possible interventions

P Kaur, S Kotru, S Singh, A Munshi - Molecular neurobiology, 2022 - Springer
Accelerating cases of diabetes worldwide have given rise to higher incidences of diabetic
complications. MiRNAs, a much-explored class of non-coding RNAs, play a significant role …