Patients with Parkinson's disease (PD) display non-motor symptoms arising prior to the
appearance of motor signs and before a clear diagnosis. Motor and non-motor symptoms …

Whole-exome sequencing of Parkinson's disease (PD) patient DNA identified single-
nucleotide polymorphisms (SNPs) in the tyrosine nonreceptor kinase-2 (TNK2) gene …

The last decade has been highlighted by the increased use of next-generation DNA
sequencing technology to identify novel human disease genes. A critical downstream part of …

Oxidative stress is a contributing factor to Parkinson's disease (PD). Considering the
prevalence of sporadic PD, environmental exposures are postulated to increase reactive …

Failure of inherently protective cellular processes and misfolded protein-associated stress
contribute to the progressive loss of dopamine (DA) neurons characteristic of Parkinson's …

Curcumin, a polyphenol derived from Curcuma longa, used as a dietary spice, has garnered
attention for its therapeutic potential, including antioxidant, anti-inflammatory, and …

On the 15th Anniversary of Disease Models & Mechanisms as a trailblazing venue for the
dissemination of discoveries pertaining to human health involving model systems, we …

Recent remarkable advances in high-throughput genotyping and next-generation DNA-
sequencing technologies have generated massive human genome sequencing datasets …

Differential RNA editing by adenosine deaminases that act on RNA (ADARs) has been
implicated in several neurological disorders, including Parkinson's disease (PD). Here, we …

Deep learning has made significant strides recently, making it a popular option for image
processing applications. However, because to similarities in color, shape, and size of fruits …