Early identification, accurate diagnosis, and treatment of silicosis
T Li, X Yang, H Xu, H Liu - Canadian respiratory journal, 2022 - Wiley Online Library
Silicosis is a global problem, and it has brought about great burdens to society and patients'
families. The etiology of silicosis is clear, preventable, and controllable, but the onset is …
families. The etiology of silicosis is clear, preventable, and controllable, but the onset is …
The role of trace elements and minerals in osteoporosis: a review of epidemiological and laboratory findings
The objective of the present study was to review recent epidemiological and clinical data on
the association between selected minerals and trace elements and osteoporosis, as well as …
the association between selected minerals and trace elements and osteoporosis, as well as …
Glycolytic reprogramming in silica-induced lung macrophages and silicosis reversed by Ac-SDKP treatment
N Mao, H Yang, J Yin, Y Li, F Jin, T Li, X Yang… - International Journal of …, 2021 - mdpi.com
Glycolytic reprogramming is an important metabolic feature in the development of pulmonary
fibrosis. However, the specific mechanism of glycolysis in silicosis is still not clear. In this …
fibrosis. However, the specific mechanism of glycolysis in silicosis is still not clear. In this …
Thalidomide alleviates pulmonary fibrosis induced by silica in mice by inhibiting ER stress and the TLR4-NF-κB pathway
Y Li, W Cai, F Jin, X Wang, W Liu, T Li, X Yang… - International Journal of …, 2022 - mdpi.com
Silicosis is the most prevalent occupational disease in China. It is a form of pulmonary
fibrosis caused by the inhalation of silicon particles. As there is no cure for the potentially …
fibrosis caused by the inhalation of silicon particles. As there is no cure for the potentially …
Ac-SDKP attenuates activation of lung macrophages and bone osteoclasts in rats exposed to silica by inhibition of TLR4 and RANKL signaling pathways
F Jin, F Geng, D Xu, Y Li, T Li, X Yang… - Journal of …, 2021 - Taylor & Francis
Background: Silica-induced inflammatory activation is associated with silicosis and various
non-respiratory conditions. The present study was designed to examine the anti …
non-respiratory conditions. The present study was designed to examine the anti …
Transcriptomic analysis identifies upregulation of secreted phosphoprotein 1 in silicotic rats
W Cai, B Zhang, T Li, F Jin, Y Li… - Experimental and …, 2021 - spandidos-publications.com
Silicosis is caused by exposure to crystalline silica and the molecular mechanism of silicotic
fibrosis remains unclear. Therefore, the present study investigated the mRNA profiles of rats …
fibrosis remains unclear. Therefore, the present study investigated the mRNA profiles of rats …
MiR-411–3p alleviates Silica-induced pulmonary fibrosis by regulating Smurf2/TGF-β signaling
X Gao, H Xu, D Xu, S Li, Z Wei, S Li, W Cai… - Experimental Cell …, 2020 - Elsevier
Occupational exposure to silica dust particles was the major cause of pulmonary fibrosis,
and many miRNAs have been demonstrated to regulate target mRNAs in silicosis. In the …
and many miRNAs have been demonstrated to regulate target mRNAs in silicosis. In the …
OC‐STAMP Overexpression Drives Lung Alveolar Epithelial Cell Type II Senescence in Silicosis
T Li, X Yang, D Xu, Z Gao, Y Gao, F Jin… - Oxidative Medicine …, 2021 - Wiley Online Library
Cellular senescence has been considered an important driver of many chronic lung
diseases. However, the specific mechanism of cellular senescence in silicosis is still …
diseases. However, the specific mechanism of cellular senescence in silicosis is still …
Minute cellular nodules as early lesions in rats with silica exposure via inhalation
Y Li, F Jin, T Li, X Yang, W Cai, S Li, X Gao, N Mao… - Veterinary …, 2022 - mdpi.com
Mechanisms of silicosis have yet to be clarified, and pathological conditions are inaccurately
described in some experimental studies on silicosis. This study was aimed at describing …
described in some experimental studies on silicosis. This study was aimed at describing …
Role of RANKL in alveolar epithelial cell regeneration: potential novel contributor to lung tissue repair
Receptor activator for NF-kappa beta (RANK) ligand (RANKL) is found in lung tissue and
elevated in lung diseases like chronic obstructive pulmonary disease (COPD), cystic fibrosis …
elevated in lung diseases like chronic obstructive pulmonary disease (COPD), cystic fibrosis …