Biofilm of Candida albicans: formation, regulation and resistance

R Pereira, RO Dos Santos Fontenelle… - Journal of Applied …, 2021 - academic.oup.com
Candida albicans is the most common human fungal pathogen, causing infections that
range from mucous membranes to systemic infections. The present article provides an …

[HTML][HTML] Antifungal drug-resistance mechanisms in Candida biofilms

J Kaur, CJ Nobile - Current opinion in microbiology, 2023 - Elsevier
Highlights•Few classes of antifungal drugs currently exist to treat fungal infections.•Infections
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …

Oral candidiasis: A disease of opportunity

T Vila, AS Sultan, D Montelongo-Jauregui… - Journal of fungi, 2020 - mdpi.com
Oral candidiasis, commonly referred to as “thrush,” is an opportunistic fungal infection that
commonly affects the oral mucosa. The main causative agent, Candida albicans, is a highly …

[HTML][HTML] Resistance of Candida to azoles and echinocandins worldwide

KE Pristov, MA Ghannoum - Clinical Microbiology and Infection, 2019 - Elsevier
Background Recently there has been an increase in Candida infections worldwide. A
handful of species in the genus Candida are opportunistic pathogens and have been known …

Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria

CW Hall, TF Mah - FEMS microbiology reviews, 2017 - academic.oup.com
Biofilms are surface-attached groups of microbial cells encased in an extracellular matrix
that are significantly less susceptible to antimicrobial agents than non-adherent, planktonic …

Candida albicans biofilms and polymicrobial interactions

NO Ponde, L Lortal, G Ramage, JR Naglik… - Critical reviews in …, 2021 - Taylor & Francis
Candida albicans is a common fungus of the human microbiota. While generally a harmless
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …

Development and regulation of single- and multi-species Candida albicans biofilms

MB Lohse, M Gulati, AD Johnson… - Nature Reviews …, 2018 - nature.com
Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

[HTML][HTML] Candida albicans biofilms: development, regulation, and molecular mechanisms

M Gulati, CJ Nobile - Microbes and infection, 2016 - Elsevier
A major virulence attribute of Candida albicans is its ability to form biofilms, densely packed
communities of cells adhered to a surface. These biofilms are intrinsically resistant to …

Molecular evolution of antifungal drug resistance

N Robbins, T Caplan, LE Cowen - Annual review of …, 2017 - annualreviews.org
The fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …

Pathogenesis of Candida albicans biofilm

C Tsui, EF Kong, MA Jabra-Rizk - FEMS Pathogens and …, 2016 - academic.oup.com
Candida albicans is the most common human fungal pathogen causing diseases ranging
from mucosal to systemic infections. As a commensal, C. albicans asymptomatically …