Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging
K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …
A review of machine learning and deep learning approaches on mental health diagnosis
Combating mental illnesses such as depression and anxiety has become a global concern.
As a result of the necessity for finding effective ways to battle these problems, machine …
As a result of the necessity for finding effective ways to battle these problems, machine …
The role of gut dysbiosis in the pathophysiology of neuropsychiatric disorders
N Anand, VR Gorantla, SB Chidambaram - Cells, 2022 - mdpi.com
Mounting evidence shows that the complex gut microbial ecosystem in the human
gastrointestinal (GI) tract regulates the physiology of the central nervous system (CNS) via …
gastrointestinal (GI) tract regulates the physiology of the central nervous system (CNS) via …
Muscarinic acetylcholine receptor agonists as novel treatments for schizophrenia
Schizophrenia remains a challenging disease to treat effectively with current antipsychotic
medications due to their limited efficacy across the entire spectrum of core symptoms as well …
medications due to their limited efficacy across the entire spectrum of core symptoms as well …
Neuroinflammation in schizophrenia: the key role of the WNT/β-catenin pathway
A Vallée - International Journal of Molecular Sciences, 2022 - mdpi.com
Schizophrenia is a very complex syndrome involving widespread brain multi-
dysconnectivity. Schizophrenia is marked by cognitive, behavioral, and emotional …
dysconnectivity. Schizophrenia is marked by cognitive, behavioral, and emotional …
[HTML][HTML] The dual hit hypothesis of schizophrenia: Evidence from animal models
Schizophrenia is a heterogeneous psychiatric disorder, which can severely impact social
and professional functioning. Epidemiological and clinical studies show that schizophrenia …
and professional functioning. Epidemiological and clinical studies show that schizophrenia …
New and emerging treatments for schizophrenia: a narrative review of their pharmacology, efficacy and side effect profile relative to established antipsychotics
MC Lobo, TS Whitehurst, SJ Kaar, OD Howes - … & Biobehavioral Reviews, 2022 - Elsevier
Schizophrenia is associated with substantial unmet needs, highlighting the necessity for
new treatments. This narrative review compares the pharmacology, clinical trial data and …
new treatments. This narrative review compares the pharmacology, clinical trial data and …
High-throughput screening platforms in the discovery of novel drugs for neurodegenerative diseases
Neurodegenerative diseases (NDDs) are incurable and debilitating conditions that result in
progressive degeneration and/or death of nerve cells in the central nervous system (CNS) …
progressive degeneration and/or death of nerve cells in the central nervous system (CNS) …
[HTML][HTML] Glycosylation and behavioral symptoms in neurological disorders
P Pradeep, H Kang, B Lee - Translational Psychiatry, 2023 - nature.com
Glycosylation, the addition of glycans or carbohydrates to proteins, lipids, or other glycans, is
a complex post-translational modification that plays a crucial role in cellular function. It is …
a complex post-translational modification that plays a crucial role in cellular function. It is …
Genome-wide Mendelian randomization identifies actionable novel drug targets for psychiatric disorders
Psychiatric disorders impose tremendous economic burden on society and are leading
causes of disability worldwide. However, only limited drugs are available for psychiatric …
causes of disability worldwide. However, only limited drugs are available for psychiatric …