[HTML][HTML] A brief review about melatonin, a pineal hormone
FG Amaral, J Cipolla-Neto - Archives of endocrinology and …, 2018 - SciELO Brasil
Melatonin is a ubiquitous molecule in nature, being locally synthesized in several cells and
tissues, besides being a hormone that is centrally produced in the pineal gland of …
tissues, besides being a hormone that is centrally produced in the pineal gland of …
Melatonin as a hormone: new physiological and clinical insights
J Cipolla-Neto, FG Amaral - Endocrine reviews, 2018 - academic.oup.com
Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …
Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas
Melatonin is an ancient antioxidant. After its initial development in bacteria, it has been
retained throughout evolution such that it may be or may have been present in every species …
retained throughout evolution such that it may be or may have been present in every species …
[HTML][HTML] Melatonin: a mitochondrial targeting molecule involving mitochondrial protection and dynamics
Melatonin has been speculated to be mainly synthesized by mitochondria. This speculation
is supported by the recent discovery that aralkylamine N-acetyltransferase/serotonin N …
is supported by the recent discovery that aralkylamine N-acetyltransferase/serotonin N …
The mitochondrial permeability transition pore: an evolving concept critical for cell life and death
G Morciano, N Naumova, P Koprowski… - Biological …, 2021 - Wiley Online Library
In this review, we summarize current knowledge of perhaps one of the most intriguing
phenomena in cell biology: the mitochondrial permeability transition pore (mPTP). This …
phenomena in cell biology: the mitochondrial permeability transition pore (mPTP). This …
Melatonin and sirtuins: a “not‐so unexpected” relationship
Epigenetic modifications, including methylation or acetylation as well as post‐transcriptional
modifications, are mechanisms used by eukaryotic cells to increase the genome diversity in …
modifications, are mechanisms used by eukaryotic cells to increase the genome diversity in …
[HTML][HTML] Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm
The brain lacks a classic lymphatic drainage system. How it is cleansed of damaged
proteins, cellular debris, and molecular by-products has remained a mystery for decades …
proteins, cellular debris, and molecular by-products has remained a mystery for decades …
[HTML][HTML] Melatonin mitigates mitochondrial meltdown: interactions with SIRT3
Melatonin exhibits extraordinary diversity in terms of its functions and distribution. When
discovered, it was thought to be uniquely of pineal gland origin. Subsequently, melatonin …
discovered, it was thought to be uniquely of pineal gland origin. Subsequently, melatonin …
[HTML][HTML] Melatonin for the treatment of sepsis: the scientific rationale
RMLC Biancatelli, M Berrill… - Journal of thoracic …, 2020 - ncbi.nlm.nih.gov
Sepsis affects 30 million people worldwide, leading to 6 million deaths every year (WHO),
and despite decades of research, novel initiatives are drastically needed. According to the …
and despite decades of research, novel initiatives are drastically needed. According to the …
Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective
A Sevilla, J Chéret, RM Slominski… - Journal of pineal …, 2022 - Wiley Online Library
The evolutionarily ancient methoxyindoleamine, melatonin, has long perplexed investigators
by its versatility of functions and mechanisms of action, which include the regulation of …
by its versatility of functions and mechanisms of action, which include the regulation of …