Wastewater-based surveillance as a tool for public health action: SARS-CoV-2 and beyond

MD Parkins, BE Lee, N Acosta, M Bautista… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Wastewater-based surveillance (WBS) has undergone dramatic advancement in the context
of the coronavirus disease 2019 (COVID-19) pandemic. The power and potential of this …

A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection

SA Narayanan, DA Jamison Jr, JW Guarnieri… - European Journal of …, 2024 - nature.com
COVID-19, the disease caused by SARS-CoV-2, has caused significant morbidity and
mortality worldwide. The betacoronavirus continues to evolve with global health implications …

Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts

JW Guarnieri, JM Dybas, H Fazelinia, MS Kim… - Science translational …, 2023 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins bind to host
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …

[HTML][HTML] Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters

M Aksu, P Kumar, T Güttler, W Taxer, K Gregor, B Mußil… - Antiviral research, 2024 - Elsevier
The ongoing threat of COVID-19 has highlighted the need for effective prophylaxis and
convenient therapies, especially for outpatient settings. We have previously developed …

Virus spreading in cruiser cabin

K Ritos, D Drikakis, IW Kokkinakis - Physics of Fluids, 2023 - pubs.aip.org
This paper concerns virus droplet simulations in a typical cruiser's cabin. Effects of
ventilation rates and positions of the coughing person were investigated. The study also …

COVID-19 biomarkers at the crossroad between patient stratification and targeted therapy: the role of validated and proposed parameters

M Rizzi, D D'Onghia, S Tonello, R Minisini… - International Journal of …, 2023 - mdpi.com
Clinical knowledge about SARS-CoV-2 infection mechanisms and COVID-19
pathophysiology have enormously increased during the pandemic. Nevertheless, because …

SARS-CoV-2 and vascular dysfunction: a growing role for pericytes

C McQuaid, A Montagne - Cardiovascular Research, 2023 - academic.oup.com
SARS-CoV-2 and vascular dysfunction: a growing role for pericytes | Cardiovascular Research
| Oxford Academic Skip to Main Content Advertisement intended for healthcare professionals …

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition

I Iacobucci, V Monaco, L Canè, F Bibbò… - Frontiers in Molecular …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus
Disease 2019 (COVID-19), which, since 2019 in China, has rapidly become a worldwide …

Ligand-based discovery of coronavirus main protease inhibitors using MACAW molecular embeddings

J Dong, M Varbanov, S Philippot, F Vreken… - Journal of Enzyme …, 2023 - Taylor & Francis
Ligand-based drug design methods are thought to require large experimental datasets to
become useful for virtual screening. In this work, we propose a computational strategy to …

SARS-CoV-2 infection in brown-headed spider monkeys (Ateles fusciceps) at a wildlife rescue center on the coast of Ecuador—South America

M Carvajal, C Saenz, N Fuentes, R Guevara… - Microbiology …, 2024 - Am Soc Microbiol
Human populations can be affected in unpredictable ways by the emergence and spread of
zoonotic diseases. The COVID-19 (coronavirus disease of 2019) pandemic was a reminder …