Ethnopharmacological relevance Portulaca oleracea L.(PO), popularly known as purslane,
has been documented in ethnopharmacology in various countries and regions. Traditional …

Pancreatic cancer (PC) is a serious gastrointestinal tract disease for which the 5-year
survival rate is less than 10%, even in developed countries such as the USA. The genomic …

Lung cancer exhibits the highest incidence and mortality rates among cancers globally, with
a five-year overall survival rate alarmingly below 20%. Targeting autophagy, though a …

A phytochemical investigation on the alkaloid fractions of Sophora alopecuroides L. led to
the production of 11 undescribed matrine-type alkaloids, sophaloseedlines I–S (1− 11), 12 …

Matrine (MAT), a natural Chinese herbal medicine, has a unique advantage in the treatment
of various chronic diseases. However, its low melting point, low bioavailability, and high …

Three highly oxidized hybrid flavonoids neosophoflavonoids A–C (1, 2a, and 2b) were
isolated from the roots of Sophora flavescens. Neosophoflavonoid A possesses a unique …

Nasopharyngeal carcinoma (NPC), primarily found in the southern region of China, is a
malignant tumor known for its highly metastatic characteristics. The high mortality rates …

Background and aims Isogarcinol, a natural compound extracted from the fruits of Garcinia
oblongifolia, has potential chemopreventive activity. This study aimed to elucidate the anti …

Despite significant advancements in multiple myeloma (MM) treatment in recent years, most
patients will eventually develop resistance or experience relapse. Matrine, a primary active …

Circular RNAs (circRNAs) are a novel class of non-coding RNAs with covalently closed
structures formed by reverse splicing of precursor mRNAs. The widespread expression of …