NF-κB Pathway and Its Inhibitors: A Promising Frontier in the Management of Alzheimer's Disease

BS Sivamaruthi, N Raghani, M Chorawala… - Biomedicines, 2023 - mdpi.com
The nuclear factor kappa B (NF-κB) pathway has emerged as a pivotal player in the
pathogenesis of various diseases, including neurodegenerative illnesses like Alzheimer's …

Neolignans in Magnolia officinalis as natural anti-Alzheimer's disease agents: A systematic review

N Li, Y Liang, L Zhang, C Xu, L Wang - Ageing Research Reviews, 2024 - Elsevier
Background Magnolia officinalis, a traditional herbal medicine widely used in clinical
practice, exerts antibacterial, anti-tumor, anti-inflammatory, antioxidant, and anti-aging …

Voglibose attenuates cognitive impairment, Aβ aggregation, oxidative stress, and neuroinflammation in streptozotocin-induced Alzheimer's disease rat model

M Rajkumar, S Kannan, R Thangaraj - Inflammopharmacology, 2023 - Springer
Alzheimer's disease (AD) is an age-dependent neurodegenerative disease hallmarked by
Amyloid-β (Aβ) aggregation, cognitive impairment, and neuronal and synaptic loss. In this …

FGF-18 alleviates memory impairments and neuropathological changes in a rat model of Alzheimer's disease

AC Ciltas, S Karabulut, B Sahin, AK Filiz, F Yulak… - Neuropeptides, 2023 - Elsevier
Alzheimer's disease (AD) is a multifactorial pathology marked by amyloid beta (Aβ)
accumulation, tau hyperphosphorylation, and progressive cognitive decline. Previous …

Banxia-Houpu decoction inhibits iron overload and chronic intermittent hypoxia-induced neuroinflammation in mice

XY Yang, JR An, QB Dong, YJ Gou, CL Jia… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance The Banxia-Houpu decoction (BHD), a renowned
prescription documented in the Chinese medical book “The Synopsis of the Golden …

Recent advances of honokiol: pharmacological activities, manmade derivatives and structure-activity relationship

X Li, Z Yuan, Y Wang, W Wang, J Shi - European Journal of Medicinal …, 2024 - Elsevier
Honokiol (HNK) is a typical natural biphenyl polyphenol compound. It has been proven to
have a wide range of biological activities, including pharmacological effects such as anti …

Libertellenone C attenuates oxidative stress and neuroinflammation with the capacity of NLRP3 inhibition

J Cao, L Li, R Zhang, Z Shu, Y Zhang, W Sun… - Natural Products and …, 2024 - Springer
Neurodegenerative diseases (NDs) are common chronic diseases arising from progressive
damage to the nervous system. Here, in-house natural product database screening revealed …

Amelioration of cognitive deficit by cryptotanshinone in a long-term utilisation of proton pump inhibitor-induced alzheimer's disease-like condition in a rat model

KR Aran, G Das Gupta, S Singh - Revista Brasileira de Farmacognosia, 2023 - Springer
Lansoprazole is a proton pump inhibitor, used to treat acid-related diseases, like reflux
esophagitis, gastric and duodenal ulcers, and Zollinger-Ellison syndrome. Cryptotanshinone …

[HTML][HTML] Croton hirtus attenuating streptozotocin-induced neuroinflammation in rats

P Ramakrishnan, J Rajangam, BV Cherian… - Digital Chinese …, 2023 - Elsevier
Objective The present study was aimed to investigate the neuroprotective effect of Croton
hirtus (CH) extract against streptozotocin (STZ) in rats. Methods (i) The sub-chronic toxicity …

Herbal Approaches for the Management of Neurological Disorders

V Yadav, S Guin, S Nayak, A Mishra - Drug Delivery Strategies in …, 2024 - Springer
Neurological disorder like epilepsy, Alzheimer's, and Parkinson's disease is manifested by
extensive morbidity, disability, along high rate of mortality, which actively compromising …