[HTML][HTML] Enzymatic synthesis of novel vitexin glucosides
Vitexin is a C-glucoside flavone that exhibits a wide range of pharmaceutical activities.
However, the poor solubility of vitexin limits its applications. To resolve this limitation, two …
However, the poor solubility of vitexin limits its applications. To resolve this limitation, two …
Biotransformation of celastrol to a novel, well-soluble, low-toxic and anti-oxidative celastrol-29-O-β-glucoside by Bacillus glycosyltransferases
TS Chang, TY Wang, CM Chiang, YJ Lin… - Journal of bioscience …, 2021 - Elsevier
Celastrol is a quinone-methide triterpenoid isolated from the root extracts of Tripterygium
wilfordii (Thunder god vine). Although celastrol possesses multiple bioactivities, the potent …
wilfordii (Thunder god vine). Although celastrol possesses multiple bioactivities, the potent …
[HTML][HTML] Postharvest Drying Techniques Regulate Secondary Metabolites and Anti-Neuroinflammatory Activities of Ganoderma lucidum
Ganoderma lucidum extract is a potent traditional remedy for curing various ailments. Drying
is the most important postharvest step during the processing of Ganoderma lucidum. The …
is the most important postharvest step during the processing of Ganoderma lucidum. The …
Novel Ganoderma triterpenoid saponins from the biotransformation-guided purification of a commercial Ganoderma extract
Highlights•A novel Biotransformation-guided purification (BGP) process was
developed.•Two novel Ganoderma saponins were identified.•Both new saponins possessed …
developed.•Two novel Ganoderma saponins were identified.•Both new saponins possessed …
[HTML][HTML] Enzymes, biocatalysis and chemical biology
S Serra - Molecules, 2020 - mdpi.com
Chemical transformations that take advantage of biocatalysis are of great interest to
chemists. The specific activity and selectivity of the enzymes allow them to perform different …
chemists. The specific activity and selectivity of the enzymes allow them to perform different …
[HTML][HTML] Glycosylation of Ganoderic Acid G by Bacillus Glycosyltransferases
Ganoderma lucidum is a medicinal fungus abundant in triterpenoids, its primary bioactive
components. Although numerous Ganoderma triterpenoids have already been identified …
components. Although numerous Ganoderma triterpenoids have already been identified …
Production of a new triterpenoid disaccharide saponin from sequential glycosylation of ganoderic acid A by 2 Bacillus glycosyltransferases
TS Chang, CM Chiang, JY Wu, YL Tsai… - Bioscience …, 2021 - academic.oup.com
Ganoderic acid A (GAA) is a lanostane-type triterpenoid, isolated from medicinal fungus
Ganoderma lucidum, and possesses multiple bioactivities. In the present study, GAA was …
Ganoderma lucidum, and possesses multiple bioactivities. In the present study, GAA was …
[HTML][HTML] Novel glycosylation by amylosucrase to produce glycoside anomers
Simple Summary All livings are composed of cells, which contain lipid, proteins, nuclei
acids, and saccharides. Saccharides include polysaccharides, oligo saccharides …
acids, and saccharides. Saccharides include polysaccharides, oligo saccharides …
[HTML][HTML] Biocatalytic Synthesis of a Novel Bioactive Ginsenoside Using UDP-Glycosyltransferase from Bacillus subtilis 168
Y Hu, H Li, Y Qu, X Zhang, J Zhang, L Dai - Catalysts, 2020 - mdpi.com
Ginsenoside Rg3 is a bioactive compound from Panax ginseng and exhibits diverse notable
biological properties. Glycosylation catalyzed by uridine diphosphate-dependent …
biological properties. Glycosylation catalyzed by uridine diphosphate-dependent …
UDP⁃ 糖基供体在中药苷类成分生物合成中的应用及研究进展
卢欣欣, 牛腾飞, 赵淑娟, 王峥涛… - 上海中医药大学 …, 2023 - shzyydxxb.shzyyzz.com
尿苷二磷酸(UDP)-糖基供体是三萜, 黄酮和蒽醌等中药活性成分糖基化修饰的重要组成前体.
近年来, 通过代谢工程策略合成苷类化合物已取得一定进展, 但UDP-糖基供体在不同类型的底盘 …
近年来, 通过代谢工程策略合成苷类化合物已取得一定进展, 但UDP-糖基供体在不同类型的底盘 …