[HTML][HTML] Recent advances in ocular graft-versus-host disease

X Cheng, R Huang, S Huang, W Fan, R Yuan… - Frontiers in …, 2023 - frontiersin.org
Ocular graft-versus-host-disease (GVHD) remains a significant clinical complication after
allogeneic hematopoietic stem cell transplantation. Impaired visual function, pain, and other …

[HTML][HTML] Challenges and concepts in the diagnosis and management of ocular graft-versus-host disease

C Tappeiner, A Heiligenhaus, JP Halter… - Frontiers in …, 2023 - frontiersin.org
Graft-versus-host disease (GVHD) is characterized by tissue inflammation in the host
following an allogeneic hematopoietic cell transplantation (HCT). The pathophysiology is …

Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria

Y Ogawa, R Dana, S Kim, S Jain, MI Rosenblatt… - The Ocular Surface, 2022 - Elsevier
Purpose To validate the international chronic ocular graft-versus-host disease (GVHD)
diagnostic criteria (ICCGVHD) compared to the National Institute of Health diagnostic criteria …

Cellular senescence promotes meibomian gland dysfunction in a chronic graft-versus-host disease mouse model

S Sato, Y Ogawa, E Shimizu, K Asai, T Okazaki… - The Ocular Surface, 2024 - Elsevier
Purpose Aging is a well-established risk factor for meibomian gland dysfunction (MGD). We
previously reported an accelerated cellular senescence phenomenon in the lacrimal glands …

[HTML][HTML] Corneal perforation associated with ocular graft-versus-host disease

Y Xu, YM Wang, ZT Sun, XL Yang, XY Zhuang… - Frontiers in …, 2022 - frontiersin.org
Corneal perforation is a rare and serious complication of ocular graft-versus-host disease
(oGVHD) patients. This study was to retrospectively report seven corneal perforation patients …

Infectious and Noninfectious Corneal Ulcers in Ocular Graft-Versus-Host Disease: Epidemiology, Clinical Characteristics, and Outcomes

PA Sepulveda-Beltran, P Carletti, V Banda… - American journal of …, 2024 - Elsevier
PURPOSE To evaluate the incidence, clinical characteristics, microbiological profile, and
therapeutic outcomes of corneal ulcers in individuals with chronic ocular graft-vs-host …

Long-term clinical outcomes and predictive factors in patients with chronic ocular graft-versus-host disease

HJ Yoon, GY Song, KC Yoon - Scientific Reports, 2022 - nature.com
We investigate long-term clinical outcomes and predictive factors associated with poor
vision outcomes in patients with ocular graft-versus-host disease (oGVHD). This …

Pathological role of inflammation in ocular disease progress and its targeting by mesenchymal stem cells (MSCs) and their exosome; current status and prospect

A Nouralishahi, N Fazlinejad, RDC Pecho… - … -Research and Practice, 2023 - Elsevier
Because of their unique capacity for differentiation to a diversity of cell lineages and
immunosuppressive properties, mesenchymal stem cells (MSC) are being looked at as a …

Tear cytokines associated with therapeutic effects in chronic ocular graft-versus-host disease

J Ma, Z Shen, R Peng, C Li, Y Zhao, B Hu, J Hong - Cornea, 2023 - journals.lww.com
Purpose: The local application of antiinflammatory and immunosuppressive agents is an
effective method for the treatment of ocular graft-versus-host disease (oGVHD); however, we …

[HTML][HTML] Microenvironment in Acute Myeloid Leukemia: Focus on senescence mechanisms, therapeutic interactions and future directions

L Guarnera, E Santinelli, E Galossi, A Cristiano… - Experimental …, 2023 - Elsevier
Acute myeloid leukemia (AML) is a disease with dismal prognosis, mainly affecting elderly
individuals. In recent years, new drugs have improved life expectancy and quality of life, and …