Epigenetics is the study of heritable changes in gene expression that occur without
alterations to the DNA sequence, linking the genome to its surroundings. The accumulation …

This study aimed to evaluate whether folic acid supplementation would improve cognitive
performance by reducing serum inflammatory cytokine concentrations. This RCT was …

Neuropsychiatric symptoms and mental illness are commonly present in patients with
chronic systemic diseases. Mood disorders, such as depression, are present in up to 50% of …

Parkinson's disease (PD) is characterized by motor impairments and progressive
dopaminergic neuronal death in the substantia nigra (SN). Recently, the involvement of …

Alzheimer's disease (AD) is the most common age-related dementia. Pathognomonic
accumulation of cerebral β-amyloid plaques likely results from imbalanced production and …

Abstract Alzheimer's disease (AD), an extremely common neurodegenerative disorder of the
older generation, is one of the leading causes of death globally. Besides the conventional …

Alzheimer's disease (AD) is a neurodegenerative disorder and the most common type of age-
related dementia. Cognitive decline, beta-amyloid (Aβ) accumulation, neurofibrillary tangles …

Resveratrol, a polyphenol phytoalexine, has been shown to play a neuroprotective role in
the neurodegenerative process in Alzheimer's disease (AD) and improve memory function in …

Alzheimer's disease (AD) is one of the most common neurodegenerative disease.
Accumulating evidences suggest an active role of inflammation in the pathogenesis of AD …

Disruption of brain-derived neurotrophic factor (BDNF) biosynthesis and/or signaling has
been implicated in the pathogenesis of Alzheimer's disease (AD). We used postmortem …