The cross-sectional association between amyloid burden and white matter hyperintensities in older adults without cognitive impairment: A systematic review and meta …
Alzheimer's disease (AD) is the most common cause of dementia, characterized by the
aggregation of amyloid-beta (Aβ) proteins into plaques. Individuals with AD frequently show …
aggregation of amyloid-beta (Aβ) proteins into plaques. Individuals with AD frequently show …
Association of white matter volume with brain age classification using deep learning network and region wise analysis
Structural magnetic resonance imaging (sMRI) has been used to examine age-related
neuroanatomical changes in the human brain. In the present work, a pre-trained deep …
neuroanatomical changes in the human brain. In the present work, a pre-trained deep …
The association between white matter hyperintensities and amyloid and tau deposition
White matter hyperintensities (WMHs) frequently occur in Alzheimer's Disease (AD) and
have a contribution from ischemia, though their relationship with β-amyloid and …
have a contribution from ischemia, though their relationship with β-amyloid and …
Sporadic cerebral small vessel disease and cognitive decline in healthy older adults: A systematic review and meta-analysis
A Jansma, J de Bresser, JW Schoones… - Journal of Cerebral …, 2024 - journals.sagepub.com
We performed a systematic review and meta-analysis on prospective studies that provided
risk estimates for the impact of 3 different MRI markers of small vessel disease (SVD) …
risk estimates for the impact of 3 different MRI markers of small vessel disease (SVD) …
White matter hyperintensity trajectories in patients with progressive and stable mild cognitive impairment
Background and Objectives White matter hyperintensities (WMH) are pathologic brain
changes that are associated with increased age and cognitive decline. However, the …
changes that are associated with increased age and cognitive decline. However, the …
Racial differences in white matter hyperintensity burden in older adults
White matter hyperintensities (WMHs) may be one of the earliest pathological changes in
aging. Race differences in WMH burden has been conflicting. This study examined if race …
aging. Race differences in WMH burden has been conflicting. This study examined if race …
White matter hyperintensity load varies depending on subjective cognitive decline criteria
Increased age and cognitive impairment is associated with an increase in cerebrovascular
pathology often measured as white matter hyperintensities (WMHs) on MRI. Whether WMH …
pathology often measured as white matter hyperintensities (WMHs) on MRI. Whether WMH …
The neuropathological landscape of small vessel disease and Lewy pathology in a cohort of Hispanic and non-Hispanic White decedents with Alzheimer disease
HP Wang, R Scalco, N Saito, L Beckett… - Acta Neuropathologica …, 2024 - Springer
Cerebrovascular and α-synuclein pathologies are frequently observed alongside Alzheimer
disease (AD). The heterogeneity of AD necessitates comprehensive approaches to …
disease (AD). The heterogeneity of AD necessitates comprehensive approaches to …
Topographical differences in white matter hyperintensity burden and cognition in aging, MCI, and AD
White matter hyperintensities (WMHs) are pathological changes that occur with increased
age and are associated with cognitive decline. Most WMH research has not examined …
age and are associated with cognitive decline. Most WMH research has not examined …
Sex differences in risk factors, burden, and outcomes of cerebrovascular disease in Alzheimer's disease populations
BACKGROUND White matter hyperintensities (WMHs) are associated with cognitive decline
and progression to mild cognitive impairment (MCI) and dementia. It remains unclear if sex …
and progression to mild cognitive impairment (MCI) and dementia. It remains unclear if sex …