A Compressive Review about Taxol®: History and Future Challenges

J Gallego-Jara, G Lozano-Terol, RA Sola-Martínez… - Molecules, 2020 - mdpi.com
Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …

The role of toll-like receptor in inflammation and tumor immunity

X Cen, S Liu, K Cheng - Frontiers in pharmacology, 2018 - frontiersin.org
Toll-like receptors (TLRs) activation enables host to recognize a large number of pathogen-
associated molecule patterns (PAMPs), ignite immune cells to discriminate between self and …

[HTML][HTML] The role of NF-κB in breast cancer initiation, growth, metastasis, and resistance to chemotherapy

E Pavitra, J Kancharla, VK Gupta, K Prasad… - Biomedicine & …, 2023 - Elsevier
Breast cancer (BC) is the second most fatal disease and is the prime cause of cancer allied
female deaths. BC is caused by aberrant tumor suppressor genes and oncogenes regulated …

Toll-like receptor stimulation in cancer: a pro-and anti-tumor double-edged sword

M Dajon, K Iribarren, I Cremer - Immunobiology, 2017 - Elsevier
Toll-like receptors (TLRs) are a family of transmembrane receptors that recognize various
pathogen-and damage-associated molecular pattern molecules playing an important role in …

[HTML][HTML] The interaction between two worlds: microRNAs and toll-like receptors

R Bayraktar, MTS Bertilaccio, GA Calin - Frontiers in immunology, 2019 - frontiersin.org
MicroRNAs (miRNAs) are critical mediators of posttranscriptional regulation via their
targeting of the imperfect antisense complementary regions of coding and non-coding …

Paclitaxel therapy promotes breast cancer metastasis in a TLR4-dependent manner

L Volk-Draper, K Hall, C Griggs, S Rajput, P Kohio… - Cancer research, 2014 - AACR
Emerging evidence suggests that cytotoxic therapy may actually promote drug resistance
and metastasis while inhibiting the growth of primary tumors. Work in preclinical models of …

Roles of toll-like receptors in cancer: a double-edged sword for defense and offense

S Basith, B Manavalan, TH Yoo, SG Kim… - Archives of pharmacal …, 2012 - Springer
Toll-like receptors (TLRs) belong to a class of pattern-recognition receptors that play an
important role in host defense against pathogens by recognizing a wide variety of pathogen …

[HTML][HTML] Inflammation and cancer

N Eiró, FJ Vizoso - World journal of gastrointestinal surgery, 2012 - ncbi.nlm.nih.gov
There is evidence supporting the hypothesis that inflammation participates in providing
conditions that lead to cancer. An unresolved inflammation due to any failure in the precise …

P53: a guardian of immunity becomes its saboteur through mutation

AD Agupitan, P Neeson, S Williams, J Howitt… - International journal of …, 2020 - mdpi.com
Awareness of the importance of immunity in controlling cancer development triggered
research into the impact of its key oncogenic drivers on the immune response, as well as …

Toll‐like receptor 4 activation in cancer progression and therapy

A Oblak, R Jerala - Journal of Immunology Research, 2011 - Wiley Online Library
Cancer immunotherapy has been the focus of intense research since the late 19th century
when Coley observed that bacterial components can contribute to cancer regression by …