Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by
progressive loss of pulmonary function. Drug-induced interstitial lung disease has been …

As an evolutionarily conserved intracellular degradation pathway, autophagy is essential to
cellular homeostasis. Several studies have demonstrated that autophagy showed an …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Activation of fibroblasts is essential for physiological tissue repair. Uncontrolled activation of
fibroblasts, however, may lead to tissue fibrosis with organ dysfunction. Although several …

Many lung diseases result in fibrotic remodelling. Fibrotic lung disorders can be divided into
diseases with known and unknown aetiology. Among those with unknown aetiology …

Pulmonary fibrosis can develop in association with genetic variants, occupational and
environmental exposures, adverse reactions to numerous medications, and many …

Aims: The NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome,
which is activated by reactive oxygen species (ROS) and repressed by autophagy, has been …

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by
accumulation of extracellular matrix (ECM) and impaired gas exchange. The pathobiological …

Since its entry into biomedical research in the first half of the twentieth century, electron
microscopy has been a valuable tool for lung researchers to explore the lung's delicate …

Aims Autophagy is an intracellular metabolic process that degrades and recycles own
constituents to maintain homeostasis and supply substrates. Disruption of collagen …