Coronaviruses (CoVs) constitute a large and diverse subfamily of positive-sense single-
stranded RNA viruses. They are found in many mammals and birds and have great …

Abstract Since Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was
identified in late 2019, the coronavirus disease 2019 (COVID-19) pandemic has challenged …

A promising approach to tackle the severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) could be small interfering (si) RNAs. So far it is unclear, which viral replication steps …

Since its inception in late December 2020 in China, novel coronavirus has affected the
global socio-economic aspect. Currently, the world is seeking safe and effective treatment …

The airways and alveoli of the human respiratory tract are lined by two distinct types of
epithelium, which are the primary targets of respiratory viruses. We previously established …

Abstract BioNTech/Pfizer's Comirnaty and Moderna's SpikeVax vaccines consist in mRNA
encapsulated in lipid nanoparticles (LNPs). The modularity of the delivery platform and the …

Highlights•Repurposing existing drugs for new diseases is cost effective and time saving.•In
silico methods are crucial for rapid drug screening in the early stages.•Machine learning …

As the COVID-19 (Coronavirus disease 19) pandemic spreads worldwide, the massive
numbers of COVID-19 patients have created a considerable healthcare burden for every …

Monoclonal antibody therapy has played an important role against SARS-CoV-2. Strategies
to deliver functional, antibody-based therapeutics with improved in vivo durability are …

The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …