[HTML][HTML] Role of estrogen receptors in health and disease

P Chen, B Li, L Ou-Yang - Frontiers in endocrinology, 2022 - frontiersin.org
Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …

Estrogen receptor signaling mechanisms

N Fuentes, P Silveyra - Advances in protein chemistry and structural …, 2019 - Elsevier
The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

Progress in the Chemistry of Tetrahydroquinolines

I Muthukrishnan, V Sridharan, JC Menendez - Chemical reviews, 2019 - ACS Publications
Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, being
widespread in nature and present in a broad variety of pharmacologically active …

The many faces of estrogen signaling

P Vrtačnik, B Ostanek, S Mencej-Bedrač, J Marc - Biochemia medica, 2014 - hrcak.srce.hr
Sažetak Estrogens have long been known as important regulators of the female
reproductive functions; however, our understanding of the role estrogens play in the human …

[HTML][HTML] Endocrine resistance in hormone receptor positive breast cancer–from mechanism to therapy

A Rani, J Stebbing, G Giamas, J Murphy - Frontiers in endocrinology, 2019 - frontiersin.org
The importance and role of the estrogen receptor (ER) pathway has been well-documented
in both breast cancer (BC) development and progression. The treatment of choice in women …

Estrogen biology: new insights into GPER function and clinical opportunities

ER Prossnitz, M Barton - Molecular and cellular endocrinology, 2014 - Elsevier
Estrogens play an important role in the regulation of normal physiology, aging and many
disease states. Although the nuclear estrogen receptors have classically been described to …

[HTML][HTML] The multifaceted mineralocorticoid receptor

E Gomez-Sanchez… - Comprehensive …, 2014 - ncbi.nlm.nih.gov
The primary adrenal cortical steroid hormones, aldosterone, and the glucocorticoids cortisol
and corticosterone, act through the structurally similar mineralocorticoid (MR) and …

Endocrine disruptors: Unravelling the link between chemical exposure and Women's reproductive health

S Hassan, A Thacharodi, A Priya, R Meenatchi… - Environmental …, 2024 - Elsevier
Abstract An Endocrine Disrupting Chemical (EDC) is any compound that disrupts the
function of the endocrine system in humans and is ubiquitous in the environment either as a …

[HTML][HTML] Does GPER Really Function as a G Protein-Coupled Estrogen Receptor in vivo?

J Luo, D Liu - Frontiers in endocrinology, 2020 - frontiersin.org
Estrogen can elicit pleiotropic cellular responses via a diversity of estrogen receptors (ERs)—
mediated genomic and rapid non-genomic mechanisms. Unlike the genomic responses …

Sex differences in vascular physiology and pathophysiology: estrogen and androgen signaling in health and disease

AC Boese, SC Kim, KJ Yin, JP Lee… - American Journal of …, 2017 - journals.physiology.org
Sex differences between women and men are often overlooked and underappreciated when
studying the cardiovascular system. It has been long assumed that men and women are …