Droplet-based digital PCR (ddPCR) and its applications

Y Hou, S Chen, Y Zheng, X Zheng, JM Lin - TrAC Trends in Analytical …, 2023 - Elsevier
As a new generation absolute quantitive PCR technique, droplet-based digital PCR
(ddPCR) provides the benefits of high sensitivity, precision, and reproducibility. A low-cost …

Multiplex molecular point-of-care test for syndromic infectious diseases

H Kim, HJ Huh, E Park, DR Chung, M Kang - BioChip Journal, 2021 - Springer
Abstract Point-of-care (POC) molecular diagnostics for clinical microbiology and virology has
primarily focused on the detection of a single pathogen. More recently, it has transitioned …

A three-in-one microfluidic droplet digital PCR platform for absolute quantitative analysis of DNA

Y Ren, J Ji, H Zhang, L Cao, J Hu, F Xu, Z Li - Lab on a Chip, 2023 - pubs.rsc.org
Droplet digital polymerase chain reaction (ddPCR) technology has found widespread
applications in the ultrasensitive analysis of nucleic acids, where integrated ddPCR …

“SMART” digital nucleic acid amplification technologies for lung cancer monitoring from early to advanced stages

Y Ren, L Cao, M You, J Ji, Y Gong, H Ren, F Xu… - TrAC Trends in …, 2022 - Elsevier
Recently, liquid biopsy based on detection of circulating nucleic acid (NA) biomarkers from
body fluids has emerged as a promising strategy for lung cancer monitoring. Considering …

A continuous polymerase chain reaction 3D spiral microreactor capable of facile and on-demand fabrication

Q Yang, W Zhou, H Li, J Huang, Z Song, L Cheng… - Analytica Chimica …, 2024 - Elsevier
Polymerase chain reaction (PCR) has been applied in many fields due to its efficient and
sensitive nucleic acid amplification capabilities [[1],[2],[3],[4]]. With the rapid development of …