Mechanical stress from haemodynamic perturbations or interventional manipulation of
epicardial coronary atherosclerotic plaques with inflammatory destabilization can release …

Sepsis is associated with high rates of mortality in the intensive care unit and accompanied
by systemic inflammatory reactions, secondary infections, and multiple organ failure …

Diabetic peripheral neuropathy (DPN) is a common diabetic complication. Chrysin (CHY)
has many biological properties but poor oral bioavailability. This study investigates the effect …

Colorectal cancer (CRC) is ranked as one of the most common malignancies with a high
death rate. It has been discovered that breviscapine can alter the progression and …

Forkhead box O3a (FOXO3a)-mediated mitochondrial dysfunction plays a pivotal effect on
cardiac hypertrophy and heart failure (HF). However, the role and underlying mechanisms of …

Aims: This study aimed to clarify that breviscapine combined with bone marrow
mesenchymal stem cells (BMSCs) treatment can reduce Aβ deposition in Alzheimer's …

The cardioprotective role of sivelestat, a neutrophil elastase inhibitor, has already been
demonstrated, but the underlying molecular mechanism remains unclear. This study aimed …

Breviscapine (Bre), an extract from Erigeron breviscapus, has been widely used to treat
cerebral ischemia but the mechanisms of its neuroprotective effects need to be clarified. The …

The present study investigated the therapeutic potential of breviscapine (Bre) in mitigating
lead (Pb)‑induced myocardial injury through activation of the nuclear factor erythroid‑2 …

Purpose Tangzhiqing formula (TZQ) is a traditional Chinese medicine prescribed to treat
lipid metabolism disorders, atherosclerosis, diabetes and diabetic cardiomyopathy …