Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management

SYC Tong, JS Davis, E Eichenberger… - Clinical microbiology …, 2015 - Am Soc Microbiol
Staphylococcus aureus is a major human pathogen that causes a wide range of clinical
infections. It is a leading cause of bacteremia and infective endocarditis as well as …

Plant natural products targeting bacterial virulence factors

LN Silva, KR Zimmer, AJ Macedo, DS Trentin - Chemical reviews, 2016 - ACS Publications
Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …

Zinc coordination sphere in biochemical zinc sites

DS Auld - Zinc biochemistry, physiology, and homeostasis: recent …, 2001 - Springer
Zinc is known to be indispensable to growth and development and transmission of the
genetic message. It does this through a remarkable mosaic of zinc binding motifs that …

Staphylococcus aureus toxins–their functions and genetics

D Grumann, U Nübel, BM Bröker - Infection, Genetics and Evolution, 2014 - Elsevier
The outcome of encounters between Staphylococcus (S.) aureus and its human host ranges
from life-threatening infection through allergic reactions to symptom-free colonization. The …

Staphylococcus aureus: the current state of disease, pathophysiology and strategies for prevention

GH Dayan, N Mohamed, IL Scully, D Cooper… - Expert review of …, 2016 - Taylor & Francis
Staphylococcus aureus is both a commensal organism and also an important opportunistic
human pathogen, causing a variety of community and hospital-associated pathologies, such …

The T Cell Response to Staphylococcus aureus

BM Broeker, D Mrochen, V Péton - Pathogens, 2016 - mdpi.com
Staphylococcus aureus (S. aureus) is a dangerous pathogen and a leading cause of both
nosocomial and community acquired bacterial infection worldwide. However, on the other …

The staphylococcal superantigen-like protein 7 binds IgA and complement C5 and inhibits IgA-FcαRI binding and serum killing of bacteria

R Langley, B Wines, N Willoughby, I Basu… - The Journal of …, 2005 - journals.aai.org
The staphylococcal superantigen-like proteins (SSLs) are close relatives of the
superantigens but are coded for by a separate gene cluster within a 19-kb region of the …

Organization of secondary lymphoid tissue and local IgE formation to Staphylococcus aureus enterotoxins in nasal polyp tissue

P Gevaert, G Holtappels, SGO Johansson, C Cuvelier… - Allergy, 2005 - Wiley Online Library
Background: Bilateral nasal polyposis (NP) is characterized by high concentrations of IgE in
NP tissue, which show no relation to the atopic status. We aimed to study the relationship …

Molecular and clinical characteristics of invasive group A streptococcal infection in Sweden

J Darenberg, B Luca-Harari, A Jasir… - Clinical infectious …, 2007 - academic.oup.com
Background. The incidence and severity of invasive group A streptococcal infection
demonstrate great variability over time, which at least, in part, seems to be related to group A …

T lymphocyte–endothelial cell interactions

J Choi, DR Enis, KP Koh, SL Shiao… - Annu. Rev. Immunol …, 2004 - annualreviews.org
▪ Abstract Human vascular endothelial cells (EC) basally display class I and II MHC-peptide
complexes on their surface and come in regular contact with circulating T cells. We propose …