Background: Schizophrenia is a complex mental disorder with a high heritability.
Dysfunction of the N-methyl-D-aspartate (NMDA)-type glutamate receptors may be involved …

Schizophrenia (SCZ) is a complex disorder that typically arises in late adolescence or early
adulthood. Age at onset (AAO) of SCZ is associated with long-term outcomes of the disease …

BACKGROUND: Antipsychotic medications are the mainstay of schizophrenia therapy but
may need to be changed over the course of a patient's illness to achieve the desired …

Background: premorbid IQ (pIQ) and age of onset are predictors of clinical severity and long-
term functioning after a first episode of psychosis. However, the additive influence of these …

Background: Schizophrenia is a psychotic condition marked by a lack of understanding of
reality and insight, that can be found in symptoms of severe mental disorders such as …

Hallucinations are a core feature of psychosis, and their severity during the acute phase of
illness is associated with a range of poor outcomes. Various clinical and sociodemographic …

To explore the potential role of circular RNAs (circRNAs) in children developing very early-
onset schizophrenia (VEOS). Total RNA was extracted from the plasma samples of 10 VEOS …

Objective Schizophrenia (SCZ) is a debilitating disease with a complex genetic cause in
which age at onset may reflect genetic vulnerability. Though there has been some …

Schizophrenia patients with an earlier age of onset have been found to have more serious
negative symptoms and cognitive deficits. Oxidative stress is thought to be implicated in …

Cognition shares substantial genetic overlap with schizophrenia, yet it remains unclear
whether such genetic effects become significant during developmental periods of elevated …